Cerezyme
Generic: imiglucerase
Manufacturer: Sanofi · Program: Genzyme's copay assistance program
Apply for AssistanceEligibility Criteria
Insurance Requirement
Patients with health insurance; insurance must cover the medication; Medicare Part D considered case by case
Residency
US residency required
Income requirements not disclosed
Program Information
Processing Time
Monthly reviews
Delivery Method
Ship to Doctor's office or specific site
Application Method
Phone
Reauthorization
Required — Case by case
Typically Required Documents
ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.
- Proof of income
- Doctor's letter of intent to treat and medical necessity
- FDA-approved diagnosis
Indicated For
Gaucher type 1, Gaucher type 3
About This Medication
# Genzyme's Copay Assistance Program Patient Guide: How to Get Cerezyme at Low or No Cost ## About This Program Genzyme's Copay Assistance Program helps eligible patients with Gaucher disease afford Cerezyme (imiglucerase), an enzyme replacement therapy used to treat non-CNS symptoms of Gaucher disease type 1 and type 3[1][7]. This program assists with out-of-pocket drug costs related to treatment, including copays, coinsurance, deductibles, and certain infusion-related costs[6]. ## Who Qualifies To be eligible for Genzyme's Copay Assistance Program, you must meet all of the following requirements: - Have an **FDA-approved diagnosis** of Gaucher disease (or other qualifying lysosomal storage disorders)[6] - Have **active health insurance** that covers Cerezyme[6] - Be a **resident of the United States**[1] - Have your physician recommend treatment with Cerezyme[6] Patients with Medicare Part D coverage are considered on a **case-by-case basis**[6]. The program is **not available** if your prescription is eligible to be reimbursed by Medicaid, Medicare (including Part D), VA, DOD, TRICARE, or other federal or state programs[1]. ## Income Eligibility Income requirements for this program are **not publicly disclosed**[6]. During the application process, you will need to provide proof of income, and the program will determine your eligibility based on your financial situation. Contact Genzyme directly at **1-800-745-4447, option 3** to discuss your specific income circumstances. ## Insurance Requirements This program is designed for patients **with active health insurance**. Your insurance must cover Cerezyme for you to qualify[6]. If you do not have insurance or your insurance has denied coverage for Cerezyme, you may be eligible for Sanofi's **Patient Assistance Program (PAP)** instead, which provides free medication[9]. Important note: You cannot submit claims for reimbursement to any third-party payer, including your insurance, FSA, HSA, or other medical savings accounts[1]. ## How to Apply ### Step 1: Gather Required Documents Before applying, collect the following: - **Proof of income** (recent tax return, pay stubs, or other financial documentation)[6] - **Doctor's letter of intent to treat** confirming that your physician recommends Cerezyme treatment[6] - **Statement of medical necessity** from your doctor explaining why Cerezyme is medically necessary for your condition[6] - **FDA-approved diagnosis documentation**[6] ### Step 2: Contact Genzyme Call Genzyme Support Services at **1-800-745-4447, option 3** to request the CareConnect Copay Program Application Form[2][6]. You can apply either on paper or online through this contact method[9]. ### Step 3: Complete and Submit Your Application Fill out the CareConnect application form completely, including: - Your personal and insurance information - Your proof of income - Your doctor's letter of intent to treat - Your doctor's statement of medical necessity - Your FDA-approved diagnosis Submit all materials to Genzyme as instructed[6]. ### Step 4: Application Review Genzyme will review your application. The program board meets **monthly** to review and discuss applications[8]. You will receive all program details upon registration[1]. ## Timeline and Delivery **Processing Time**: Applications are reviewed on a **monthly basis**[8]. After approval, Genzyme will ship your medication as soon as possible[8]. **Delivery Method**: Cerezyme is shipped to your doctor's office or the specific treatment site where you receive your infusions[6]. **Maximum Benefit**: The program provides assistance up to the program maximum, which varies depending on your out-of-pocket costs[1]. ## What Happens If Your Application Is Denied If you are denied from the Copay Assistance Program, you have several options: 1. **Patient Assistance Program (PAP)**: If you don't have insurance or your insurance denies coverage, you may qualify for Sanofi's Patient Assistance Program, which provides free Cerezyme[9]. 2. **Appeal**: Work with your doctor to submit an appeal letter to Genzyme, providing additional medical or financial information that supports your case[2]. 3. **Contact Sanofi Case Managers**: Call 1-800-745-4447, option 3, to discuss your situation with a case manager who can help explore other options[9]. ## Reauthorization and Refills This program requires **reauthorization**. Refills are determined on a **case-by-case basis**, and you will need to reapply periodically to continue receiving assistance[6]. Contact Genzyme to learn about the reauthorization timeline and process for your specific situation. ## Important Limitations - This program is **not valid where prohibited by law, taxed, or restricted**[1] - Sanofi reserves the right to rescind, revoke, terminate, or amend this program at any time without notice[1] - This is considered a **temporary funding program**[6] - You cannot claim reimbursement through insurance, FSA, HSA, or other medical savings accounts[1] ## Contact Information **Genzyme Support Services** - Phone: **1-800-745-4447, option 3** - Address: Genzyme Corporation, 500 Kendall St., Cambridge, MA 02142 - Website: www.cerezyme.com ## Disclaimer This guide provides general information about Genzyme's Copay Assistance Program as of March 2026. Program eligibility, benefits, and terms are subject to change at any time. Always verify current program details by contacting Genzyme directly at 1-800-745-4447, option 3, or visiting www.cerezyme.com. This information is not a guarantee of eligibility or assistance. Your healthcare provider should be involved in all discussions about your treatment and financial assistance options.
Program information last verified: March 30, 2026
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