Cathflo Activase

Indicated For

Central venous access device occlusion, catheter dysfunction

About This Medication

# Genentech Access to Care Foundation Patient Guide: How to Get Cathflo Activase (alteplase) at Low or No Cost Cathflo Activase (alteplase) is a prescription medication used to restore function to central venous access devices (CVADs) clogged by blood clots. The **Genentech Access to Care Foundation** provides this medicine at no cost to eligible uninsured patients with household incomes at or below $100,000, helping restore catheter patency without financial burden.[1][6] ## About Cathflo Activase (alteplase) Cathflo Activase is a tissue plasminogen activator (tPA) that breaks down blood clots blocking catheters, such as those used for chemotherapy, dialysis, or nutrition. Administered by a healthcare professional via direct injection into the clogged catheter, it typically works within 30-120 minutes. Common uses include clearing occlusions in PICC lines, ports, and tunneled catheters. It's FDA-approved for patients aged 2 years and older when standard flushing fails. Always follow your doctor's instructions, as it's not for arterial clots or active internal bleeding.[1] ## Who Qualifies? The program targets **uninsured US patients** (no private insurance or Medicare Part D) prescribed participating Genentech medicines like Cathflo Activase, with financial need based on household income and size. Key groups include: - Uninsured patients with **household income under specified thresholds** (e.g., under $100,000 for individuals).[6][7] - Must be treated by a US-licensed physician; no citizenship required.[6] **Income Eligibility Breakdown** Eligibility hinges on **gross annual household income** (often Adjusted Gross Income or AGI) and household size. Provide accurate figures from tax returns or pay stubs. | Household Size | Maximum Annual Income | |----------------|------------------------| | 1 person | $100,000 | | 2 people | $125,000 | | 3 people | $125,000 | | 4+ people | $150,000* | *Some exceptions may apply; call (888) 941-3331 to confirm.[6] Deductions like certain taxes may adjust AGI. Use the online Confirm Financial Eligibility tool if unsure.[3] ## Insurance Requirements **Uninsured patients only.** No eligibility for Medicare Part D enrollees. Patients with commercial insurance may qualify separately via Genentech Access Solutions if out-of-pocket costs exceed 7.5% of income, but the Foundation is strictly for uninsured.[3][6] Contact Genentech Access Solutions at (866) 422-2377 for insured options.[5] ## Step-by-Step Application Process Applying is straightforward with **multiple methods**. Both patient and prescriber forms are required; submit together for fastest processing.[1][6] 1. **Discuss with your doctor**: Confirm Cathflo Activase prescription and request they complete the **Prescriber Foundation Form** (includes medical necessity statement).[1][4] 2. **Complete Patient Consent Form**: Fill out online (English/Spanish), print/sign, or use eSubmit. Provide household size, income, DOB, ZIP.[1][9] 3. **Gather proof of income**: Recent tax returns, W-2s, pay stubs, or benefit letters.[7] 4. **Submit forms**: - **Online**: eSubmit at GenentechPatientFoundation.com or My Patient Solutions.[1][10] - **Fax**: (833) 999-4363.[1][6] - **Text photo**: (650) 877-1111.[1][8] - **Phone help**: (800) 530-3083 or (888) 941-3331.[3] 5. **Doctor submits their form**: Via fax, eSubmit, or My Patient Solutions.[4] **Required Documents**: - Doctor-completed enrollment/statement of medical necessity forms. - Patient Authorization and Notice of Information Form. - Proof of income. - Letter of medical necessity from physician.[1][6] ## Timeline and Delivery Applications process in **5 business days** after receiving both forms. Your doctor's office and you will be contacted with outcomes/next steps.[1][7] If approved, medicine ships free to your **home or physician's office**.[6] Reauthorization needed for refills/ongoing therapy.[1] ## Alternatives if Denied - **Appeal**: Contact the Foundation for clarification; resubmit missing info.[1] - **Genentech Access Solutions**: For insured patients, co-pay help, or coverage navigation (866-422-2377).[5][6] - **Other programs**: PAN Foundation, HealthWell Foundation (check eligibility for alteplase).[3] - **Patient Access Network (PAN)**: Similar income-based aid for catheter clearance meds. - **Speak to a specialist**: Call (888) 941-3331 for multilingual support and alternatives.[3] ## Disclaimer This guide summarizes the Genentech Access to Care Foundation based on available info as of 2026. Eligibility/rules may change; always verify with Genentech at (800) 530-3083 or gene.com/patients. Not medical/financial advice—consult your doctor and advisor. Genentech not liable for application errors. Program for US residents only.[1][6]

Program information last verified: March 30, 2026