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Oncology

Calquence

Generic: acalabrutinib

Manufacturer: AstraZeneca  ·  Program: Calquence Patient Savings Program

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Eligibility Criteria

Insurance Requirement

Commercially insured patients only; not available to patients with federally funded insurance plans

Residency

US residents and Puerto Rico residents

Program Information

Processing Time

4–8 weeks

Delivery Method

Varies by program

Application Method

Multiple

Typically Required Documents

ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.

  • Valid prescription
  • Enrollment form

Indicated For

Chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL)

About This Medication

# Calquence Patient Savings Program Patient Guide: How to Get Calquence at Low or No Cost Calquence (acalabrutinib) is a targeted oral therapy used to treat certain types of blood cancers, and the **Calquence Patient Savings Program** from AstraZeneca helps eligible patients access it for as low as $0 per 30-day supply. This guide explains everything you need to know in simple terms, from eligibility to applying, so you can focus on your health.[1] ## About Calquence (Acalabrutinib) **Calquence** is a prescription medicine known as a Bruton's tyrosine kinase (BTK) inhibitor. It works by blocking enzymes that cause certain white blood cells called B cells to multiply uncontrollably, which can lead to cancers like chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). It's also approved for mantle cell lymphoma (MCL) in adults who have received prior therapy.[1] Taken as capsules twice daily, Calquence is often a long-term treatment. Without assistance, costs can exceed $10,000 per month, making programs like this vital for affordability. Always take it as prescribed by your healthcare provider (HCP) and discuss any side effects, such as bleeding risks, infections, or heart rhythm changes.[1] ## Who Qualifies for the Program? This program is straightforward: it's **for U.S. residents (including Puerto Rico) with commercial insurance** who have a valid prescription for Calquence. You don't need to meet specific income thresholds—it's not needs-based. However, it's **not for patients with government or federally funded insurance** like Medicare, Medicaid, VA, DOD, TRICARE, or similar plans.[1] Key qualifications: - Valid Calquence prescription from your doctor. - Commercial (private) insurance coverage. - U.S. or Puerto Rico resident. - Enrolled via form or online.[1] If you qualify, you could pay **$0 for a 30-day supply**. The program covers the medication cost only—not doctor visits, labs, or other expenses.[1] ## Income Eligibility Breakdown Great news: **There are no income limits!** Unlike many assistance programs, the Calquence Patient Savings Program is not based on your household income. It's designed for any eligible commercially insured patient, regardless of earnings. This makes it accessible to a broad range of people facing high out-of-pocket costs. | Eligibility Factor | Details | |--------------------|---------| | **Income Threshold** | None required—open to all qualifying insured patients[1] | | **Household Size** | Not applicable | | **Annual Income Limit Example** | N/A (not needs-based)[1] | | **Other Financial Checks** | None; focuses on insurance type[1] | This no-income-requirement approach simplifies things, but confirm your insurance type with your plan provider.[1] ## Insurance Requirements **Commercial insurance only**. This means private plans from employers, marketplaces like Healthcare.gov, or individual policies—not government programs. The program won't work if you're on Medicare Part D, Medicaid, or other federal plans. If your coverage changes to a federal plan, you'll lose eligibility.[1] Why? Federal rules (Anti-Kickback Statute) prevent manufacturers from subsidizing government-insured meds. Check your insurance card: if it says something like Blue Cross, UnitedHealthcare, or Aetna (non-government), you likely qualify. Call the program at (844) 275-2360 to verify.[1] ## Step-by-Step Application Process Applying is easy with **multiple options**. Expect quick activation—often same-day for pharmacy use. Here's how: 1. **Get Your Prescription**: Ask your doctor for a Calquence prescription if it's right for you. 2. **Choose Application Method**: - **Online**: Visit https://www.calquencesavings.com/. Your HCP can enroll you digitally—fastest option.[1] - **Phone**: Call (844) 275-2360 (1-844-ASK-A360), Mon-Fri 8 AM–8 PM ET (holidays excluded).[1] - **Fax with Doctor**: Complete the enrollment form with your HCP and fax to 1-844-329-2360.[1] 3. **Gather Documents**: - Valid Calquence prescription. - Completed enrollment form (includes patient and doctor signatures).[1] 4. **Submit**: Online or phone is instant; fax takes 1-2 days. You'll get a savings card for the pharmacy. 5. **Use at Pharmacy**: Present the card with your insurance and prescription. Pay $0 for up to 30-day supply (max savings per fill apply; check terms).[1] The offer is valid for claims up to 365 days from service date.[1] ## Timeline and Delivery - **Processing**: Online/phone: immediate savings card. Fax: 24-48 hours.[1] - **Delivery**: No home delivery—use your pharmacy. Pick up like regular meds.[1] - **Duration**: Covers ongoing fills as long as eligible (up to 12 months typical; auto-renews in some cases—no reauthorization needed).[1] - **Refills**: Show savings card each time; valid through expiration. Track via the website or phone support.[1] ## Alternatives if Denied or Ineligible Denied? Common reasons: federal insurance, expired Rx, or non-U.S. resident. Options: - **Switch Insurance**: If possible, explore commercial plans. - **Other AstraZeneca Programs**: Check manufacturer site for bridge programs. - **Patient Access Networks (PAN) or HealthWell**: Needs-based copay help (income limits apply). - **NeedyMeds or RxAssist**: Search for CLL/MCL funds. - **Generic/Biosimilars**: None yet for acalabrutinib. - **Pharmacy Discounts**: GoodRx for uninsured (still costly). - **Clinical Trials**: Ask your doctor.[1] Contact a social worker or call 211 for local help. ## Important Disclaimer This guide is for informational purposes based on program details as of 2026 and is not medical or financial advice. Eligibility, terms, and availability can change—always verify with AstraZeneca at (844) 275-2360 or https://www.calquencesavings.com/. Consult your doctor before starting Calquence. Program covers med cost only; other expenses are your responsibility. AstraZeneca reserves rights to modify/amend/terminate. Not valid where prohibited by law.[1] (Word count: 1028)

Program information last verified: March 30, 2026

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