BRUKINSA
Generic: zanubrutinib
Manufacturer: BeOne Medicines · Program: myBeOne Support
Apply for AssistanceEligibility Criteria
Insurance Requirement
Commercial insurance (employer-sponsored or individual plans including Aetna, Cigna, Blue Cross Blue Shield, Humana); uninsured; underinsured; Medicare Part D
Residency
US resident
Program Information
Processing Time
1 business day
Delivery Method
Shipped to patient or physician office
Application Method
Phone
Typically Required Documents
ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.
- Completed enrollment form signed by prescriber and patient
- Prescription (NPI# 1699202838 for eScript)
- Copy of front and back of insurance card (if seeking insurance verification)
Indicated For
Chronic lymphocytic leukemia (CLL), Small lymphocytic lymphoma (SLL), Waldenström macroglobulinemia (WM), Marginal zone lymphoma (MZL)
About This Medication
# myBeOne Support Patient Guide: How to Get BRUKINSA (zanubrutinib) at Low or No Cost BRUKINSA (zanubrutinib) is a prescription medication used to treat certain types of blood cancers, and the **myBeOne Support** program from **BeOne Medicines** helps eligible patients access it at low or no cost through free medication, co-pay assistance, bridge supplies, and more.[1][2][3] This guide explains everything you need to know in simple terms, from who qualifies to how to apply step-by-step. ## About BRUKINSA (zanubrutinib) **BRUKINSA** is an oral kinase inhibitor that targets specific proteins in cancer cells to help stop their growth. It's approved for adults with certain lymphomas, like mantle cell lymphoma (MCL), Waldenström's macroglobulinemia (WM), and chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).[2][6][9] You take it as capsules, usually once or twice daily, with or without food, but always follow your doctor's instructions on dosing to stay on schedule.[2] Common side effects can include diarrhea, bruising, rash, and low blood cell counts, but your doctor will monitor you closely. myBeOne Support Oncology Nurse Advocates can answer questions about how to take it, tips for adherence, and what to discuss with your doctor.[2][6] ## Who Qualifies for myBeOne Support? The program helps a wide range of patients prescribed BRUKINSA, with **no financial requirements** for some benefits like bridge supply or initial insurance help.[2] Key groups include: - **Commercially insured** patients (employer-sponsored or individual plans like Aetna, Cigna, Blue Cross Blue Shield, Humana) for co-pay support up to **$25,000 per year**—eligible patients may pay **$0 per prescription**.[2][3] - **Uninsured** (no insurance or denied coverage) or **underinsured** (high out-of-pocket costs) for **free BRUKINSA** if you meet financial criteria.[2][3][4] - **Medicare Part D, VA, DoD, TriCare** patients—referred to independent foundations for co-pay help (program doesn't cover government insurance directly).[2] - Anyone facing insurance delays gets a **free 30-day bridge supply** if delay is 5+ days.[2][3] **Oncology Nurse Advocates** provide personalized support, including insurance verification, prior authorizations, appeals, and connections to day-to-day resources like counseling or transportation.[1][2][3] ## Income Eligibility Breakdown For **free product assistance** (BRUKINSA at no cost), uninsured or underinsured patients must meet financial criteria, though exact income thresholds aren't publicly detailed—call (833) 234-4363 for your situation.[2][3][4] Commercial co-pay has **no income limits**.[2] Here's a simple table summarizing eligibility: | Patient Type | Key Benefits | Financial Requirements | Insurance Type | |--------------|--------------|------------------------|---------------| | Commercial (e.g., Aetna, Cigna, BCBS, Humana) | Co-pay support up to $25,000/year ($0 per Rx) | None | Employer/individual plans [2][3] | | Uninsured/underinsured | Free BRUKINSA | Meets certain criteria (call to confirm) | None/denied coverage [2][3][4] | | Medicare/VA/DoD/TriCare | Referrals to foundations | Varies by foundation | Government plans [2] | | Insurance delay | 30-day bridge supply | None | Any [2][3] | ## Insurance Requirements - **Accepted**: Commercial plans (including Aetna, Cigna, Blue Cross Blue Shield, Humana); uninsured; underinsured; Medicare Part D.[2] - Program verifies coverage, handles prior auths/appeals.[1][2] - Government insurance: Referred to independent 501(c)(3) foundations—program provides info but doesn't decide eligibility.[2][3] - First-time co-pay: Call (833) 234-4363 (Mon-Fri 8AM-8PM ET) to activate—no card needed.[2][3] ## Step-by-Step Application Process Applications are by **phone**—no online form for patients, but HCPs can enroll via site.[1][4] Processing takes **1 business day**.[program details] 1. **Get your prescription**: Ask your doctor for BRUKINSA (use NPI# 1699202838 for eScripts).[program details] 2. **Call myBeOne Support**: Dial **(833) 234-4363** (Mon-Fri 8AM-8PM ET). Speak to an Oncology Nurse Advocate—they guide you.[1][2][3] 3. **Complete enrollment**: Doctor and you sign the form. Provide: - Prescription - Insurance card copy (front/back, if applicable) [program details] 4. **Advocate assesses**: Insurance check, financial review, benefit assignment (co-pay, free med, bridge).[2] 5. **Approval**: Usually **1 business day**—medication **shipped to you or doctor's office**.[program details][1] Fax option for forms: 1-877-828-5593 (if directed).[4] ## Timeline and Delivery - **Phone support**: Mon-Fri 8AM-8PM ET.[2][3] - **Processing**: 1 business day.[program details] - **Bridge**: 30-day supply for 5+ day delays.[2][3] - **Delivery**: Shipped free to patient or physician office.[program details] - Ongoing: Advocate follows up for refills, questions.[2] ## Alternatives if Denied - **Appeal insurance** with advocate help.[1][2] - **Independent foundations** for co-pays (Medicare etc.).[2][3] - **State programs** or other resources—advocate connects you.[2] - **Other PAPs**: Check ACCC guide or call for referrals.[4] If ineligible, advocate suggests next steps like financial aid orgs.[2] ## Disclaimer myBeOne Support is not insurance and doesn't guarantee coverage. Eligibility varies; independent orgs set their rules—BeOne Medicines not involved.[2][3][6] Consult your doctor; this isn't medical advice. Program details may change—call (833) 234-4363 for latest info. Word count: 942.
Program information last verified: March 25, 2026
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