BRIXADI

Indicated For

Opioid Use Disorder, OUD

About This Medication

# BRIXADI Copay Savings Program Patient Guide: How to Get BRIXADI at Low or No Cost BRIXADI (buprenorphine) extended-release injection is an FDA-approved treatment for moderate to severe opioid use disorder (OUD), offered through a **Copay Savings Program** by Braeburn Pharmaceuticals for eligible commercially insured patients. This guide explains how to access financial help to reduce your out-of-pocket costs for BRIXADI, a weekly or monthly subcutaneous injection that provides steady buprenorphine release as part of a comprehensive treatment plan including counseling.[2][4][8] ## About BRIXADI **BRIXADI** is a prescription medication used to treat moderate to severe opioid addiction (OUD) in adults who have initiated treatment with a single dose of transmucosal buprenorphine (sublingual tablet or buccal film) or are already on buprenorphine therapy. It comes in weekly (8 mg, 16 mg, 24 mg, 32 mg) or monthly (64 mg, 96 mg, 128 mg) subcutaneous injections, administered only by healthcare providers in a healthcare setting due to the Brixadi REMS program, which ensures safe use and prevents risks like intravenous misuse.[2][4][6][8] Unlike daily pills or films, BRIXADI offers continuous release without daily fluctuations, helping maintain steady treatment levels. It must be combined with counseling and behavioral therapy for best results. Common side effects include injection-site pain, headache, constipation, nausea, and more. Always discuss risks, like serious breathing problems, with your doctor, and carry naloxone for emergencies.[2][4] BRIXADI is distributed through a limited network of specialty pharmacies, so your doctor will send the prescription there.[3][5] ## Who Qualifies for the Copay Savings Program? The **BRIXADI Copay Savings Program** is designed for **commercially insured patients** (private insurance, not government-funded). Key eligibility: - **Commercial/Private Insurance**: Eligible if your plan covers BRIXADI (not Medicaid, Medicare, VA, DoD, TRICARE, or other federal/state programs).[2][3] - **No Government Insurance**: Patients on Medicaid or Medicare are ineligible for copay savings but may have low copays ($4-$8) where Medicaid covers BRIXADI.[2][3] - **State Restrictions**: Void where prohibited by law.[3] - **Income**: No specific income thresholds listed; program focuses on insurance type rather than FPL limits.[2][3][5] Uninsured or self-pay patients may explore other options, but this program is copay-focused. Braeburn ByYourSide can help check coverage.[3] ## Income Eligibility Breakdown Unlike traditional patient assistance programs with strict FPL limits, the BRIXADI Copay Savings Program does not specify income thresholds. It prioritizes commercial insurance status. Here's a summary: | Household Size | Income Threshold | FPL % | Notes | |---------------|------------------|-------|-------| | Individual | Not specified | N/A | Commercial insurance required; no FPL limit mentioned.[3] | | Couple | Not specified | N/A | Same as above. | | Family of 3 | Not specified | N/A | Focus on insurance type, not income.[2][3] | | Family of 4 | Not specified | N/A | Excludes government programs. | For comparison, some buprenorphine programs limit to 300%-400% FPL, but BRIXADI's is insurance-based.[7] Contact Braeburn for personalized eligibility.[3] ## Insurance Requirements - **Commercial Insurance Only**: Must have private insurance covering BRIXADI. Provide your copay ID number at the specialty pharmacy for savings.[3][5] - **Medicaid**: Often covers with low copays ($4-$8) in many states; ineligible for copay program.[2] - **Medicare**: Ineligible for copay savings.[3] - **Prior Authorization (PA)**: May be needed; Braeburn ByYourSide assists with PA and appeals.[3] - **Specialty Pharmacy**: Prescription goes to an authorized pharmacy in the limited network.[3][5] ## Step-by-Step Application Process 1. **Talk to Your Doctor**: Confirm BRIXADI is right for you. They must initiate with transmucosal buprenorphine if new to treatment.[2][4] 2. **Enroll in Copay Program**: Two ways: - **Self-Enroll**: Visit the copay savings website, register, and get your copay ID number.[2][3][5] - **Doctor Enrolls**: Download the Copay Enrollment Handout or use the Braeburn portal/HCP site.[3] 3. **Provide Copay ID**: Give the ID to your doctor or specialty pharmacy to apply savings.[5] 4. **Prescription Handling**: Doctor sends Rx to a BRIXADI specialty pharmacy.[3] 5. **Call for Support**: Contact Braeburn ByYourSide at **877-279-7367** (M-F, 8AM-8PM ET) for coverage checks, PA help, or questions. Fax enrollment to 877-335-2294.[3] 6. **Receive Treatment**: Get injected at your healthcare provider's office.[6][8] ## Timeline and Delivery - **Processing**: Varies by insurance/PA; Braeburn assists to speed up. No fixed timeline stated, but copay activation is quick upon enrollment.[3][5] - **Delivery**: No home delivery—administered in-office by providers via specialty pharmacy fulfillment.[3][5][6] - **Dosing Schedule**: Weekly or monthly injections; steady-state reached over time.[4][8] ## Alternatives if Denied or Ineligible - **Medicaid**: Check state coverage (low copays possible).[2] - **Other Assistance**: General drug savings sites or state programs.[5] - **Patient Assistance**: No free drug program noted for uninsured; explore SAMHSA Helpline (1-800-662-HELP) for OUD resources.[1] - **Biosimilars/Alternatives**: No biosimilars listed. Other buprenorphine options like Sublocade may have programs.[6][7] - **Appeals**: Braeburn helps with insurance appeals.[3] ## Important Disclaimer This guide is for informational purposes only and not a substitute for medical or financial advice. Eligibility, terms, and availability can change; program void where prohibited. Costs vary by insurance, pharmacy, and location. Always consult your healthcare provider, pharmacist, or Braeburn ByYourSide (877-279-7367) for personalized help. See full Prescribing Information, Medication Guide, and BOXED WARNING for risks. Report side effects to Braeburn (1-833-274-9234) or FDA (1-800-FDA-1088).[2][3][4]

Program information last verified: March 30, 2026