Breyanzi

Indicated For

Large B-cell lymphoma, Chronic lymphocytic leukemia, Small lymphocytic lymphoma, Follicular lymphoma, Mantle cell lymphoma, Marginal zone lymphoma

About This Medication

# Cell Therapy 360 Patient Guide: How to Get Breyanzi (lisocabtagene maraleucel) at Low or No Cost Breyanzi (lisocabtagene maraleucel) is a **CAR T-cell therapy** developed by Bristol Myers Squibb to treat certain types of large B-cell lymphoma (LBCL) in adults who have received prior treatments. The **Cell Therapy 360** program offers financial assistance through a Copay Assistance Program, covering out-of-pocket costs for the drug itself for eligible commercially insured patients, along with personalized support like navigators and logistical help.[1][5][10] ## About Breyanzi and CAR T-Cell Therapy **Breyanzi** is an innovative immunotherapy where your own T-cells (a type of immune cell) are collected, genetically modified in a lab to target cancer cells, and infused back into your body. It's approved for adults with relapsed or refractory LBCL after at least two prior lines of therapy, including disease progression after certain treatments.[3][10] This one-time infusion therapy can provide durable responses for many patients, but it's complex and requires treatment at a certified CAR T-cell therapy center.[8] The process involves: - **Leukapheresis**: Collecting your T-cells. - **Manufacturing**: Engineering the cells (takes about 3-4 weeks). - **Lymphodepleting chemotherapy**: Prepares your body. - **Infusion**: Receiving the modified cells. - **Monitoring**: Close follow-up for side effects like cytokine release syndrome (CRS) or neurological events.[1][6] Cell Therapy 360 supports you through every step, from enrollment to post-infusion monitoring.[3] ## Who Qualifies for Cell Therapy 360 Copay Assistance? This program is designed for patients prescribed Breyanzi who need help with costs. Key qualifications include: - Prescription from a healthcare provider at a **certified CAR T-cell therapy treatment center**.[5][8] - **Commercially insured** (private insurance); **not eligible** if on Medicare, Medicaid, TRICARE, VA, or other federal/state programs.[1][5] - **Income-based eligibility**: Specific thresholds aren't publicly detailed, but the program considers household income with additional requirements applying.[1] - Willingness to enroll via your provider or by contacting the program.[5] **Additional perks** for eligible patients: - Dedicated **Patient Support Navigator** available 24/7 for questions.[1][5] - **Logistical support**: Possible help with transportation, lodging, and meals for you and a caregiver.[4][6] Always confirm eligibility, as Bristol Myers Squibb may change terms.[1] ## Income Eligibility Breakdown Cell Therapy 360 uses income-based criteria tied to Federal Poverty Level (FPL), though exact percentages aren't specified publicly. Here's a general overview based on similar programs (contact the program for your situation): | Household Size | Estimated Max Annual Income (300% FPL example)* | Notes | |---------------|------------------------------------------------|-------| | Individual | ~$45,180 | Income-based; varies by program rules[1] | | Couple | ~$61,320 | Additional eligibility applies | | Family of 3 | ~$77,460 | *Illustrative; call for exacts | | Family of 4 | ~$93,600 | Excludes government insurance | *Hypothetical based on 2026 FPL guidelines; actual thresholds require verification via (888) 805-4555. Program covers drug copays only, not other costs.[1][5] ## Insurance Requirements **Strictly for commercially insured patients**. The Copay Assistance Program reduces or eliminates out-of-pocket costs for Breyanzi itself but: - Excludes Medicare, Medicaid, TRICARE, VA, or any government programs.[1][5][10] - Does **not** cover non-drug costs like hospital stays, provider fees, or other treatments.[1] - Use the **Insurance Lookup Tool** on celltherapy360.com to check coverage.[1] If uninsured or underinsured, explore other BMS resources or independent foundations.[2] ## Step-by-Step Application Process 1. **Get Prescribed**: Your doctor at a certified center determines Breyanzi is right for you.[3][5] 2. **Find a Center**: Use the CAR T Treatment Center Locator on celltherapy360.com.[1][8] 3. **Enroll in Cell Therapy 360**: Provider enrolls you, or call **(888) 805-4555** (press 1 for patients). Provide insurance and income details.[5] 4. **Submit Info**: Share proof of commercial insurance, income (e.g., tax returns, pay stubs), and prescription.[1] 5. **Approval**: Navigator guides you; copay card issued if eligible.[10] 6. **Proceed to Treatment**: Drug ships to your physician's office.[1] Applications start by phone—no online form listed.[5] ## Timeline and Delivery - **Enrollment to Approval**: Varies; call for personalized timeline. Manufacturing takes ~3-4 weeks post-collection.[6] - **Delivery**: Breyanzi ships frozen directly to the certified treatment center/physician office.[1] - **Support Ongoing**: Navigator available 24/7 through monitoring period.[1] Processing times depend on insurance verification and eligibility review.[2] ## Alternatives if Denied or Ineligible - **Independent Foundations**: Apply to Patient Access Network (PAN), HealthWell, or CancerCare for copay help. - **Manufacturer Free Drug Programs**: Ask about BMS compassionate use if income too high/low. - **State Programs**: Check for lymphoma-specific aid. - **Clinical Trials**: Search clinicaltrials.gov for Breyanzi studies. - **Appeal**: Contact navigator to review denial reasons.[1] No biosimilars available for this CAR T therapy.[1] ## Important Disclaimer This guide is for informational purposes only and not a guarantee of coverage. Eligibility, benefits, and program rules can change; Bristol Myers Squibb reserves the right to amend/revoke without notice. Consult your doctor, navigator, or call (888) 805-4555 for latest details. Not medical/financial advice. Word count: 1028.[1][5]

Program information last verified: March 30, 2026