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Oncology

Braftovi

Generic: encorafenib

Manufacturer: Pfizer Inc.  ·  Program: Pfizer Patient Assistance Program

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Eligibility Criteria

Insurance Requirement

Uninsured or commercially insured without government programs (Medicare, Medicaid, etc.)

Residency

US resident

Income Threshold

Up to 400% FPL

Individual Income Limit

$75,000/year

At or below 400% FPL, adjusted for family size; excludes government insurance

Program Information

Processing Time

2-4 weeks

Delivery Method

shipped to patient or physician office

Application Method

Multiple

Reauthorization

Required — annual

Typically Required Documents

ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.

  • proof of income
  • proof of residency
  • prescription
  • insurance status

Indicated For

BRAF V600 melanoma, BRAF V600E metastatic colorectal cancer

About This Medication

# Pfizer Patient Assistance Program Patient Guide: How to Get Braftovi (encorafenib) at Low or No Cost Braftovi (encorafenib) is a prescription medication used to treat certain types of cancer, such as melanoma and colorectal cancer with specific genetic mutations. The **Pfizer Patient Assistance Program** helps eligible patients get Braftovi at low or no cost if they meet income and insurance criteria[1][5]. ## About Braftovi (encorafenib) **Braftovi** is a targeted therapy drug that belongs to a class of medications called BRAF inhibitors. It works by blocking enzymes in cancer cells that promote tumor growth, specifically in patients whose tumors have the BRAF V600E or V600K mutation. It's FDA-approved for: - Unresectable or metastatic melanoma (often combined with Mektovi, binimetinib). - BRAF V600E-mutant metastatic colorectal cancer (with cetuximab). Common side effects include fatigue, nausea, diarrhea, and skin issues. Always take it as prescribed by your doctor, and report side effects promptly. This program provides free medication to qualifying patients, easing financial burdens during treatment[1][5][10]. ## Who Qualifies for the Program? The Pfizer Patient Assistance Program is for U.S. residents (or U.S. territories) aged 18+ with a valid prescription from a licensed U.S. healthcare provider. Key requirements include: - **Income eligibility**: Household income at or below **400% of the Federal Poverty Level (FPL)**, adjusted for family size. Excludes those with government insurance like Medicare or Medicaid. - **Insurance status**: Uninsured or commercially insured without coverage for the medication (government programs disqualify most applicants). - FDA-approved diagnosis. - Unable to afford the medication after exploring other options. Proof of U.S. residency is required, but citizenship is not[5]. ## Income Eligibility Breakdown Eligibility is based on pre-tax annual household income. Use the table below to check if you qualify (2026 FPL guidelines; confirm current levels at application). | Household Size | Max Income (400% FPL) | |----------------|-----------------------| | 1 (Individual) | $75,000 | | 2 (Couple) | $100,000 | | 3 | $125,000 | | 4 | $150,000 | | +1 per member | +$25,000 | **Notes**: Income includes wages, Social Security, pensions. Provide proof like tax returns (1040), W-2s, pay stubs, or SSA-1099. Electronic verification is optional[2][4]. ## Insurance Requirements - **Eligible**: Uninsured or commercially insured patients denied coverage (after appeal) or unable to afford copays/out-of-pocket costs. - **Not eligible**: Medicare, Medicaid, VA, Tricare, or other government programs. Commercially insured patients generally ineligible unless specific exceptions apply[2][5][10]. Medicare Part D patients may need to enroll in the Medicare Prescription Payment Plan first and attest inability to pay[6]. ## Step-by-Step Application Process 1. **Check eligibility**: Visit www.PfizerRxPathways.com, use the Program Finder, enter "Braftovi"[1][5]. 2. **Gather documents**: - Proof of income (tax return, W-2, pay stubs). - Proof of residency (utility bill, etc.). - Valid prescription. - Insurance info (cards, denial letter if applicable)[4]. 3. **Complete application**: - **Online (preferred)**: Use Pfizer PAP Connect at pfizerpapconnect.com. New patients create account; upload docs[3][8]. - **Phone**: Call (800) 505-4426 for help or manual forms[1]. - **Mail/Fax**: Download form, have doctor complete/sign, send to P.O. Box 66585, St. Louis, MO 63166-6585 or fax 866-470-1748/1-877-548-1734[4][10]. 4. **Doctor involvement**: Prescriber confirms diagnosis, fills section 14 on form[10]. 5. **Sign consents**: Patient signs for income verification, HIPAA, etc.[2]. Applications support multiple methods for accessibility[1][3]. ## Timeline and Delivery - **Processing**: 2-4 weeks (typically 2-3). You'll get a letter with status[1][4]. - **Delivery**: Free medication shipped to your home or doctor's office. Enrollment lasts 1 year; reauthorization needed[1]. Track status via Pfizer PAP Connect[3]. ## Alternatives if Denied - **Appeal**: Contact program if income/insurance misread. - **Other programs**: Pfizer Oncology Together for copay help (insured patients), state assistance, or generic/biosimilar options (none for Braftovi currently). - **RxPathways**: Explore via PfizerRxPathways.com for 500+ programs. - **Medicaid/State exchanges**: Apply if eligible. - **Manufacturer copay cards**: For commercially insured[5][9]. ## Reauthorization and Refills Reauthorization required annually. Enrolled patients request refills via PAP Connect, phone (800) 505-4426, or mail. Provide updated income/proof[3][8]. ## Disclaimer This guide is for informational purposes based on program details as of 2026. Eligibility rules change; always verify at PfizerRxPathways.com or call (800) 505-4426. Not medical/financial advice—consult your doctor. Pfizer may verify income electronically. Program offered by Pfizer Inc. and Pfizer Patient Assistance Foundation; free meds not taxable[2][5]. (Word count: 1028)

Program information last verified: March 30, 2026

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