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Oncology

Blincyto

Generic: blinatumomab

Manufacturer: Amgen  ·  Program:

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Eligibility Criteria

Insurance Requirement

Commercial/private insurance for co-pay program; uninsured referred to foundations

Residency

US resident

No manufacturer PAP identified; refers to independent foundations for uninsured

Program Information

Processing Time

4–8 weeks

Delivery Method

Varies by program

Application Method

Multiple

Indicated For

B-cell precursor acute lymphoblastic leukemia (ALL)

About This Medication

# Amgen SupportPlus Patient Guide: How to Get BLINCYTO® (blinatumomab) at Low or No Cost BLINCYTO® (blinatumomab) is a prescription immunotherapy used to treat certain types of B-cell precursor acute lymphoblastic leukemia (ALL) in adults and children one month and older. Amgen SupportPlus offers financial help through a **co-pay program** for patients with commercial/private insurance and referrals to independent foundations for uninsured patients[1][5][6]. ## About BLINCYTO® and Who It Helps BLINCYTO® is a **bispecific T-cell engager** that helps your immune system target and kill leukemia cells expressing CD19. It is FDA-approved for: - Consolidation treatment in Philadelphia chromosome-negative (Ph-) B-cell precursor ALL. - Minimal residual disease (MRD) ≥0.1% in first or second complete remission. - Relapsed or refractory B-cell precursor ALL[1][4]. Treatment involves continuous intravenous infusion over cycles: typically 28 days on, followed by treatment-free periods (14 or 56 days depending on the regimen). Doses are weight-based for patients under 45 kg or fixed for those 45 kg and over. Premedication with steroids like dexamethasone or prednisone is required to reduce risks like cytokine release syndrome (CRS)[4]. **Important Safety Note:** BLINCYTO® has boxed warnings for CRS, neurological toxicities (e.g., immune effector cell-associated neurotoxicity syndrome or ICANS), and infections. Discuss risks with your doctor[1][4]. ## Who Qualifies for Amgen SupportPlus? Amgen SupportPlus tailors support to your insurance: - **Commercial/Private Insurance:** Eligible for the **Amgen SupportPlus Co-Pay Program**. Pay as little as **$0 per dose** for deductibles, co-insurance, and co-pays. **No income requirements**[1][3][5][9]. - **Uninsured or No Commercial Insurance:** No direct manufacturer patient assistance program (PAP). Amgen refers you to **independent nonprofit foundations** that may cover medication costs[1][3]. - **Government Insurance (e.g., Medicare, Medicaid):** Generally ineligible for co-pay program; explore foundations or state programs[1]. There are **no specific income thresholds** listed for Amgen programs, as the co-pay card has none. Foundations may have their own rules, often based on federal poverty level (FPL), such as 400-500% FPL[1]. ### Income Eligibility Breakdown | Insurance Type | Program | Income Eligibility | Coverage Details | |---------------|---------|---------------------|------------------| | **Commercial/Private** | Co-Pay Program | **None required** | $0 out-of-pocket per dose (terms apply); covers deductible/co-pay/co-insurance[1][9] | | **Uninsured** | Foundation Referral | Varies by foundation (often ≤400-500% FPL) | Full or partial medication cost; Amgen provides info[1][3] | | **Medicare/Medicaid** | Not eligible for co-pay; foundations | Varies | Check Medicare Extra Help or foundations[1] | | **Underinsured** | Co-Pay + Foundations | As above | Co-pay for commercial portions; foundations for gaps | **Notes:** Eligibility for co-pay has program maximums and terms—visit AmgenSupportPlus.com/Copay. Foundations require applications separately[1][9]. ## Insurance Requirements - **Must have commercial/private insurance** (e.g., employer-sponsored or marketplace plans) for co-pay program[1][5]. - **Medicare patients ineligible** for co-pay; Amgen SupportPlus can guide to other resources[1]. - Uninsured patients get foundation referrals—no insurance needed for those[1][3]. Your doctor or Amgen SupportPlus can verify benefits via phone[1][7]. ## Step-by-Step Application Process 1. **Talk to Your Doctor:** Confirm BLINCYTO® prescription. Ask them to contact Amgen SupportPlus for benefits verification or prior authorization help (866-264-2778)[1][7]. 2. **Check Eligibility:** - Commercial insurance: Enroll in co-pay program at AmgenSupportPlus.com/copay or call (866) 264-2778[1][6][9]. - Uninsured: Request foundation info from Amgen SupportPlus[1]. 3. **Enroll Online or by Phone:** - Visit www.amgensupportplus.com/patient/blincyto[6]. - Call **(866) 264-2778** for Patient Navigator support[1]. Provide insurance details, income (if needed for foundations), and prescription info. 4. **Submit Documents:** Minimal for co-pay (proof of commercial insurance, pharmacy details). Foundations may need income proof (tax returns, pay stubs), proof of no insurance, and doctor's statement[1]. 5. **Pharmacy Coordination:** Amgen helps with prior authorizations and home infusion if needed[1][3]. ## Timeline and Delivery - **Co-Pay Approval:** Often instant upon enrollment; savings apply at pharmacy[9]. - **Foundation Assistance:** 1-4 weeks typical for independent programs (varies)[1]. - **Delivery:** Prescription filled at specialty pharmacy or infusion center. Amgen coordinates home infusion agencies if applicable[3]. Processing time not specified—call for updates[1]. Refills: Co-pay card valid per terms; re-enroll or reapply for foundations as needed[1]. ## Alternatives if Denied or Ineligible - **Switch Programs:** If co-pay denied, try foundations via Amgen referral[1]. - **Patient Access Networks (PAN) Foundation, HealthWell Foundation, or Leukemia & Lymphoma Society:** Common for ALL drugs; apply online. - **State Assistance Programs:** Check for your state. - **Clinical Trials:** Ask oncologist about BLINCYTO® trials. - **Biosimilars:** None available[ ]. - **Generic Alternatives:** None; BLINCYTO® is brand-only. Contact Amgen SupportPlus for personalized options[1][6]. ## Disclaimer This guide is for informational purposes based on publicly available data as of 2026. Programs change; **always verify with Amgen SupportPlus at (866) 264-2778 or AmgenSupportPlus.com**. Not medical advice—consult your healthcare provider. Eligibility, terms, and availability vary. Amgen does not guarantee coverage. See full BLINCYTO® Prescribing Information for safety[1][4]. (Word count: 1028)

Program information last verified: March 25, 2026

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