BIVIGAM

Indicated For

primary humoral immunodeficiency (PI)

About This Medication

# ADMA ADvantage Ig Patient Support Program Patient Guide: How to Get BIVIGAM (immune globulin intravenous (human) 10%) at Low or No Cost BIVIGAM is an intravenous immune globulin (IVIG) medication used to treat primary humoral immunodeficiency (PI) in adults and children aged 2 years and older, helping boost the immune system by providing antibodies to fight infections.[1][6] The **ADMA ADvantage Ig Patient Support Program** from **ADMA Biologics** offers financial assistance to eligible, commercially insured patients by covering up to **$6,000 per year** in out-of-pocket costs for BIVIGAM after your first $75 payment, making treatment more affordable.[6] ## About BIVIGAM **BIVIGAM** is a 10% immune globulin intravenous (human) solution derived from human plasma. It replaces antibodies your body may lack due to PI, a condition where the immune system doesn't produce enough of these protective proteins. Administered by infusion in a doctor's office, hospital, or at home under medical supervision, it helps prevent infections like pneumonia, sinusitis, and bronchitis. Common side effects include headache, fatigue, and infusion-site reactions; serious risks like allergic reactions or blood clots require immediate medical attention. Always follow your doctor's instructions and report side effects.[1][3] ## Who Qualifies for the Program? This program targets **commercially insured patients** (private insurance, not government programs like Medicare or Medicaid) prescribed BIVIGAM who are U.S. residents (including Puerto Rico).[6] It's **not income-based**, so financial hardship isn't a barrier—focus is on insurance type and residency. You must enroll and agree to program terms, including sharing health information with ADMA Biologics. Patients pay the first **$75** of deductible, copay, coinsurance, or administration costs per treatment; the program then covers up to $6,000 annually total. It excludes office/facility fees not directly tied to BIVIGAM or other non-drug costs.[6][1] **Income Eligibility Breakdown** Since eligibility isn't tied to income, there's no Federal Poverty Level (FPL) threshold. However, here's a general guide to U.S. income contexts for reference (2026 guidelines; check HHS.gov for updates): | Household Size | 100% FPL | 400% FPL (Common Private Insurance Threshold) | Program Note | |---------------|----------|---------------------------------------------|--------------| | Individual | $15,060 | $60,240 | No income limit[6] | | Couple | $20,440 | $81,760 | No income limit[6] | | Family of 3 | $25,820 | $103,280 | No income limit[6] | | Family of 4 | $31,200 | $124,800 | No income limit[6] | The program prioritizes access over finances, unlike free drug programs requiring <400-500% FPL.[6] ## Insurance Requirements **Commercial insurance required**—no coverage for Medicare, Medicaid, VA, Tricare, or uninsured patients.[6] The program verifies benefits, checks prior authorizations, and handles appeals to maximize your coverage. It covers copays, deductibles, coinsurance, and some administration after your $75 initial payment. Submit Explanation of Benefits (EOB) or pharmacy invoices within **120 days** of treatment for reimbursement.[1][6] Government-insured? Seek alternatives like manufacturer free drug programs or nonprofits.[4] ## Step-by-Step Application Process 1. **Get Prescribed**: Ask your doctor for BIVIGAM if appropriate for your PI. 2. **Discuss Support**: Your prescriber completes part of the enrollment form, requesting services like benefits verification, prior auth help, or copay assistance.[1][6] 3. **Fill Enrollment Form**: Download from bivigam.com or call (833) 236-2246. Provide: name, phone, email, last 4 SSN digits, DOB, gender, address, US residency yes/no. Check services needed (e.g., Benefits Verification, Copay Program). Sign patient certification consenting to terms and data sharing.[1] 4. **Submit**: Doctor faxes to (833) 216-0441 or use DocuSign/PDF options. Mail to PO Box 503278, San Diego, CA 92150.[1][2][6] 5. **Program Reviews**: They verify eligibility, investigate benefits (often same-day if before 2 PM ET), and contact you.[4] 6. **Pay First $75**: At infusion, pay initial out-of-pocket; submit EOB/invoice for rest.[6] Call **(833) 236-2246** (Mon-Fri, 9 AM-6 PM ET) for help—1-833-ADMA-BIO.[1] ## Timeline and Delivery - **Benefits Verification**: Same day if requested by 2 PM ET; 24-48 hours otherwise.[4][8] - **Enrollment Processing**: Quick after fax; expect welcome contact.[1] - **Reimbursement**: Submit docs within 120 days; processed promptly.[6] - **Delivery**: BIVIGAM ships via specialty pharmacy or infuses at site. Program doesn't handle delivery but coordinates insurance/pharmacy.[4] Refills follow same EOB process; annual $6,000 cap resets yearly.[6] ## Alternatives if Denied or Ineligible - **Appeal**: Program assists with denials/claims.[1][4] - **Other Foundations**: Patient Access Network (PAN), HealthWell—check eligibility for IVIG. - **Government Insured**: State programs, 340B clinics, or ADMA's other options.[4] - **Uninsured**: Nonprofit PAPs like NeedyMeds or RxAssist. - **Biosimilars/Alternatives**: None listed; discuss ASCENIV (same maker, similar program) or generics with doctor.[4] ## Important Disclaimer This guide summarizes publicly available info as of 2026; terms change—verify with ADMA at (833) 236-2246 or bivigam.com.[1][6] Not medical/financial advice. Eligibility per program rules; ADMA decides. Covers only specified costs; other expenses yours. Consult doctor/insurer. ADMA Biologics reserves rights to amend/discontinue.[1]

Program information last verified: March 30, 2026