Bevyxxa

Indicated For

VTE prophylaxis

About This Medication

# Bevyxxa Patient Guide: How to Get Bevyxxa at Low or No Cost **Important Notice: Bevyxxa (betrixaban) has been discontinued by the manufacturer in April 2020 and is no longer available in the US market.** This guide provides information for historical reference or if limited supplies exist through special channels, but patients should consult their healthcare provider for current alternatives like other anticoagulants (e.g., Eliquis or enoxaparin).[1][8] ## About Bevyxxa Bevyxxa (betrixaban) is an oral anticoagulant, often called a blood thinner, used to prevent venous thromboembolism (VTE)—blood clots in the veins—in adults hospitalized for acute medical illnesses with risk factors like moderate to severe restricted mobility.[2][3] Approved by the FDA in June 2017, it was indicated for short-term use: an initial 160 mg dose followed by 80 mg once daily with food for 35-42 days.[3][6] For those with severe renal impairment or on certain P-gp inhibitors, dosing reduces to 80 mg initial then 40 mg daily.[2][6] **Key benefits** from the APEX trial (7,513 patients): Bevyxxa reduced VTE risk compared to shorter enoxaparin therapy (4.4% vs. 6.0% incidence), without significantly increasing major bleeding.[3][6] However, it carries risks of serious bleeding, so it's not for patients with active bleeding, certain spinal procedures, or those who've exceeded 42 days of therapy.[2] Since discontinuation, no manufacturer-sponsored patient assistance program (PAP) exists, as Portola Pharmaceuticals ceased production for business reasons.[1] Focus shifts to general low-cost options like Medicare support or alternatives.[1][4] ## Who Qualifies for Assistance? No specific Bevyxxa PAP exists due to discontinuation. Instead, explore these options: - **Medicare Part D patients**: Use the Medicare Prescription Payment Plan (started 2025) to spread out-of-pocket costs (including deductibles) monthly, avoiding upfront payments. No savings, but helps with high early-year costs. Catastrophic coverage kicks in after $2,000 out-of-pocket, covering 100% of meds afterward.[1] - **Extra Help/Low-Income Subsidy (LIS)**: Federally funded for Part D enrollees. Qualifies if income/assets below thresholds (e.g., ~$22,590 individual/$30,660 couple in 2025; check annually). Benefits: $0 premiums/deductibles, low copays (~$4.50 generics, $12.15 brands).[1] - **Uninsured or underinsured**: Generic alternatives or hospital/clinic programs may help, but Bevyxxa stock is unavailable.[4][8] ## Income Eligibility Breakdown Bevyxxa PAP: **N/A (discontinued)**. For Medicare Extra Help (most relevant option): | Household Size | Annual Income Limit (100% FPL, approx. 2025) | Assets Limit (excl. home/car) | |----------------|----------------------------------------------|-------------------------------| | Individual | $15,060 | $17,550 | | Couple | $20,440 | $35,000 | | Family of 3 | $25,820 | $35,000 | | Family of 4 | $31,200 | $35,000 | *Notes: Limits rise ~3-5% yearly; add ~$6,380 per extra member. Apply via SSA; full details at ssa.gov/extrahelp. Not exact for Bevyxxa but applies to Part D meds.[1]* ## Insurance Requirements - **Medicare Part D**: Primary option. Payment Plan open to all; Extra Help for low-income. No PAP copay cards due to discontinuation.[1] - **Commercial/Private Insurance**: Prior authorization often required (e.g., failure of Eliquis/Xarelto, no active bleeding).[2] Check coverage; high copays possible pre-2025 redesign. - **Medicaid/Uninsured**: State programs or free clinics for alternatives; Bevyxxa unavailable.[4] ## Step-by-Step Application Process 1. **Confirm Availability**: Verify with pharmacist/doctor if any Bevyxxa remains (unlikely).[1][8] 2. **Assess Medicare Options**: - Enroll in Part D if not already. - Apply for Extra Help: Online (ssa.gov/extrahelp), call 1-800-772-1213, or mail SSA-1020 form.[1] 3. **Join Payment Plan**: At pharmacy, opt-in for monthly billing (no cost to join).[1] 4. **Seek Alternatives**: Doctor may switch to Eliquis (PAP via 1-855-ELIQUIS) or enoxaparin.[7] 5. **General PAP Search**: Use PAN Foundation or NeedyMeds for similar meds.[4] No specific Bevyxxa forms/phones/URLs exist.[1] ## Timeline and Delivery - **Extra Help Approval**: 45-90 days; retroactive if eligible.[1] - **Payment Plan**: Immediate at pharmacy. - **Delivery**: Standard pharmacy pickup; no special shipping for discontinued drug. Treatment duration fixed at 35-42 days; no refills.[2][3] ## Alternatives if Denied or Unavailable - **Switch Meds**: Enoxaparin (shorter course), Eliquis (PAP: 1-855-ELIQUIS, >90% copay help).[7] Xarelto also common.[2] - **Extra Help Appeal**: If denied, reapply with updated income proof.[1] - **State Assistance**: RxRelief or 340B clinics for low-income.[4] - **Patient Access Networks**: Grants for copays on alternatives.[4] ## Disclaimer This guide is for informational purposes only and not medical/financial advice. Bevyxxa is discontinued; consult your doctor for alternatives. Eligibility/rules change; verify with SSA/Medicare (1-800-MEDICARE). Bleeding risks high—discuss with provider. Word count: 912.

Program information last verified: March 30, 2026