BERINERT

Indicated For

Hereditary Angioedema (HAE)

About This Medication

# BERINERT Co-Pay Program Patient Guide: How to Get BERINERT at Low or No Cost BERINERT (C1 Esterase Inhibitor (Human)) is a vital treatment for acute attacks of hereditary angioedema (HAE), a rare genetic condition causing severe swelling in areas like the face, hands, feet, abdomen, or throat.[2][3] The **BERINERT Co-Pay Program** from **CSL Behring** helps eligible patients aged 12 and older reduce out-of-pocket costs for this medication, covering up to $12,000 per year in copays when obtained through a specialty pharmacy.[1][8] ## Who Qualifies for the Program? This program is designed for **U.S. residents insured in the U.S.** who are **age 12 or older** and prescribed BERINERT for HAE attacks.[1][8] You must have **commercial insurance**; patients on government programs like **Medicare, Medicaid, or Veterans Health Insurance are not eligible**.[7][8] No specific income thresholds are required, making it accessible to a broad range of insured patients facing high copays.[1] ### Income Eligibility Breakdown Unlike needs-based programs, the BERINERT Co-Pay Program does **not** have income limits. Here's a simple table summarizing eligibility: | Eligibility Factor | Details | |--------------------|---------| | **Age** | 12 years or older | | **Residency** | U.S. residents (including Puerto Rico for some related programs) | | **Insurance** | U.S. commercial insurance; **excludes Medicare, Medicaid, VA** | | **Income** | No limits (not needs-based) | | **Prescription** | BERINERT via specialty pharmacy | | **Annual Benefit** | Up to $12,000 in copay assistance per year[1][8] | This focus on insured patients ensures quick access without financial disclosures.[9] ## About BERINERT and Hereditary Angioedema (HAE) **BERINERT** is a human-derived C1 esterase inhibitor that replaces the missing or dysfunctional protein in HAE patients, helping to stop acute swelling attacks on-demand.[2][3][6] HAE affects about 1 in 50,000 people and can cause life-threatening swelling, often without hives or itching. Administered intravenously by a healthcare professional or trained patient/caregiver, a typical dose is 20 units per kg of body weight during an attack.[4] Common side effects include headache, nausea, and injection site reactions—discuss risks with your doctor.[2] The Co-Pay Program coordinates with your specialty pharmacy to cover copays, ensuring you can focus on treatment rather than costs.[5][8] ## Insurance Requirements You need **valid U.S. commercial insurance** covering BERINERT. The program performs a **benefits investigation** to confirm eligibility and copay details.[1][3] Attach copies of your **insurance card (both sides)** and **pharmacy card (both sides)** during enrollment.[1][4] Government insurance disqualifies you, but the program offers **BERINERT Connect** support for prior authorizations and other assistance.[2][4] If your plan requires prior authorization (PA), your doctor can submit it via portals like Availity.[6] ## Step-by-Step Application Process 1. **Contact BERINERT Connect**: Call **1-877-236-4423** (Monday–Friday, 8 AM–8 PM ET) to start. They'll guide you and your doctor.[1][2][4] 2. **Complete Enrollment Form**: Your prescriber fills out the **BERINERT Referral Form** with your details (name, DOB, weight, allergies, ICD-10 code), insurance info, prescription, and signature. You sign the **Patient Services Authorization and Release of Health Information** to enroll in support programs.[4] 3. **Gather Documents**: - Insurance card (both sides) - Pharmacy card (both sides) - Patient authorization form[1][4] 4. **Submit**: Fax the form to **1-866-415-2162**. The program reviews and conducts benefits verification.[1][4] 5. **Approval and Activation**: Once approved, copay assistance activates at your specialty pharmacy—**no separate card needed**.[5][8] Enrollment links you to **BERINERT Connect** for ongoing support, including voicemail permissions if desired.[2][4] ## Timeline and Delivery Processing varies, but benefits investigation happens quickly after fax submission.[1] First copay assistance often starts within days of approval, with medication **shipped to you or your pharmacy** via specialty channels.[1][6] Refills are seamless as long as you're reauthorized. Call for status updates.[2] Shipments arrive on schedule, typically 2-4 weeks for initial setup in related services.[10] ## Alternatives if Denied or During Coverage Gaps If denied (e.g., due to government insurance), explore **CSL Behring Assurance Program** for insurance lapses—it provides points for continuous therapy, redeemable during gaps (call 800-676-4266).[9] Uninsured/underinsured may qualify for other CSL programs or third-party options like Prescription Hope ($60/month flat fee, income under $200k).[7][10] Discuss biosimilars or alternatives like Ruconest with your doctor, though none are specified here.[6] Always reapply or appeal via your insurer.[6] ## Reauthorization **Reauthorization is required** annually or as benefits change. The program notifies you; resubmit updated forms to continue up to $12,000/year coverage.[1] ## Important Disclaimer This guide is for informational purposes only and not a substitute for professional medical or financial advice. Program terms, eligibility, and benefits can change—verify with CSL Behring at 1-877-236-4423 or Berinert.com. Coverage up to $12,000/year is subject to terms and conditions; not all copays may qualify. Consult your healthcare provider for treatment decisions. CSL Behring does not guarantee approval.[1][2][5][8] (Word count: 1028)

Program information last verified: March 30, 2026