BEQVEZ

Indicated For

hemophilia B

About This Medication

# Pfizer GeneTogether Patient Assistance Program: Beqvez Patient Guide: How to Get BEQVEZ (fidanacogene elaparvovec-dzkt) at Low or No Cost BEQVEZ is a one-time gene therapy approved by the FDA for adults with moderate to severe hemophilia B who currently use factor IX (FIX) prophylaxis therapy, or have current or historical life-threatening hemorrhage, or repeated serious spontaneous bleeding episodes, and do not have neutralizing antibodies to AAVRh74var capsid.[6] The **Pfizer GeneTogether Patient Assistance Program** helps eligible patients—those who are uninsured or publicly insured and meet income guidelines—access BEQVEZ at low or no cost by providing financial assistance for the drug product.[2] ## About BEQVEZ and Hemophilia B Hemophilia B is a rare genetic bleeding disorder caused by a deficiency in factor IX, a protein needed for blood clotting. Patients often require regular intravenous infusions of FIX multiple times a week or month, which can be burdensome.[6] **BEQVEZ** (fidanacogene elaparvovec-dzkt) is a groundbreaking one-time infusion gene therapy designed to help your body produce its own FIX, potentially reducing bleeding episodes and the need for ongoing treatments.[6][8] In clinical trials like BENEGENE-2, patients saw their annualized bleeding rate drop from about 4.43 bleeds per year on FIX prophylaxis to 1.30 bleeds post-treatment.[8] **Important notes:** BEQVEZ is for adults only and requires testing to confirm no pre-existing antibodies to the AAVRh74var capsid. It's administered in a medical facility, and Pfizer offers a warranty program for payers based on treatment durability to ensure access.[6][8] Always discuss with your doctor if BEQVEZ is right for you. ## Who Qualifies for the Program? The Pfizer GeneTogether Patient Assistance Program for BEQVEZ is for U.S. residents (including Puerto Rico, U.S. Virgin Islands, and Guam) who: - Have a valid prescription for BEQVEZ for an FDA-approved use. - Are treated by a licensed U.S. healthcare provider in an outpatient setting. - Are **uninsured or publicly insured** (e.g., Medicare or Medicaid).[2][7] - **Meet income guidelines** (specific percentages of the Federal Poverty Level, or FPL, apply; see table below).[2][7] **Patients with commercial insurance are not eligible.**[2] The program provides financial assistance for the gene therapy drug itself, reducing or eliminating costs for qualifying patients.[2] ## Income Eligibility Breakdown Eligibility is based on household income relative to the **Federal Poverty Level (FPL)**. Exact thresholds aren't publicly detailed but are needs-based and verified during application. Patients must submit proof of income.[2][7] Here's a general guide based on common Pfizer programs (confirm exacts via phone): | Household Size | Income Limit (e.g., ~400-500% FPL, typical for gene therapies)* | |----------------|-------------------------------------------------------------| | 1 (Individual) | Up to ~$60,000-$75,000 annually | | 2 (Couple) | Up to ~$80,000-$100,000 annually | | 3 | Up to ~$100,000-$125,000 annually | | 4 | Up to ~$120,000-$150,000 annually | *Estimates; actual limits vary by program and year. Call 888-733-2030 for your situation. Adjustments for larger households.[2][7] ## Insurance Requirements - **Eligible:** Uninsured, Medicare, Medicaid, or other public insurance.[2][5] - **Not eligible:** Commercial/private insurance plans.[2] - Medicare Part D patients may need to enroll in the voluntary Medicare Prescription Payment Plan first.[7] - The program helps with benefits verification, prior authorizations, and appeals.[3] ## Step-by-Step Application Process 1. **Get Prescribed:** Confirm with your doctor that BEQVEZ is appropriate and complete AAVRh74var antibody testing.[6] 2. **Contact Pfizer GeneTogether:** Call **1-888-733-2030** (M-F, 8 AM-8 PM ET) for a Patient Case Manager to guide you.[2][3] 3. **Complete Enrollment:** Your healthcare provider (HCP) fills out the **BEQVEZ Enrollment Form** (available at www.pfizergenetogether.com or via Accredo).[3] Opt-in for support like refill reminders and financial aid.[3] 4. **Submit Documents:** Fax to 1-646-862-9653, mail to 600 Emerson Road, 3rd Floor, Suite 300, Creve Coeur, MO 63141, or submit online.[3] Include proof of income (e.g., W-2, tax return, pay stubs).[7] 5. **Verification:** Pfizer reviews eligibility, income, and insurance. They may assist with prior auth if needed.[3] 6. **Approval Notification:** Expect contact once processed.[2] ## Timeline and Delivery Processing time varies but typically occurs within days to weeks after complete submission; call for status updates.[2][3] As a one-time gene therapy, **delivery** is coordinated directly to your infusion center via specialty pharmacy like Accredo.[3] Pfizer GeneTogether provides logistical support, including reimbursement help.[6] ## Alternatives if Denied or Ineligible - **Pfizer RxPathways:** Broader program for free Pfizer meds if uninsured/government-insured and income-eligible (1-866-706-2400).[1][4][7] - **Copay Savings Cards:** For commercially insured (check PfizerForAll.com).[4][5] - **Other Assistance:** State programs, hemophilia foundations, or PAN Foundation. - **Appeal:** Request review or reapply with updated info.[3] - No biosimilars available yet for this gene therapy.[6] ## Disclaimer This guide is for informational purposes only and based on publicly available data as of 2026. Program details, income limits, and eligibility can change; always verify with Pfizer at 1-888-733-2030 or www.pfizergenetogether.com. Not medical advice—consult your healthcare provider. Pfizer does not guarantee approval. Word count: 1028.

Program information last verified: March 30, 2026