AYVAKIT

Indicated For

GIST, Systemic Mastocytosis

About This Medication

# YourBlueprint Patient Assistance Program Guide: Getting AYVAKIT at Low Cost ## What is the YourBlueprint Patient Assistance Program? The YourBlueprint Patient Assistance Program helps patients afford AYVAKIT (avapritinib), a prescription medication used to treat gastrointestinal stromal tumors (GIST) and systemic mastocytosis. If you're struggling to pay for AYVAKIT, this program may help you get the medication you need at little to no cost. ## Who Can Apply? You may qualify for assistance if you: - Have a valid prescription for AYVAKIT from your doctor - Have no health insurance, limited insurance coverage, or unaffordable out-of-pocket costs - Meet the program's income requirements The program doesn't penalize you based on insurance status. Whether you're uninsured, underinsured, or your insurance doesn't cover AYVAKIT well, you can apply. ## Income Eligibility Income limits vary depending on your household size and circumstances. Blueprint Medicines evaluates each application individually, so your specific income threshold may differ from others. During the application process, you'll provide your household income information, and the program will determine if you qualify. Generally, the program is designed to help patients with modest to moderate incomes who would otherwise struggle to afford their medication. If you're unsure whether your income qualifies, submit an application anyway—the program staff can clarify your eligibility. ## What You'll Need to Apply Before starting your application, gather: - A valid prescription for AYVAKIT from your healthcare provider - Proof of income (recent tax return, pay stubs, or benefit statements) - Proof of citizenship or residency - Insurance information (if applicable) - Contact information and identification Having these documents ready will speed up the application process. ## How to Apply: 4 Steps **Step 1: Contact the Program** Call YourBlueprint Patient Assistance at **(888) 258-7768** to request an application. You can also visit the program website at https://ayvakit.com/indolent-systemic-mastocytosis/patient-support-program/ for additional information and to potentially start your application online. **Step 2: Complete Your Application** Fill out all required sections with accurate information. You'll be asked about your medical condition, current medications, household income, and insurance status. The program accepts applications through multiple channels—phone, mail, or online—whichever is easiest for you. **Step 3: Submit Supporting Documents** Provide proof of income and other documentation the program requests. The more complete your application, the faster it can be reviewed. **Step 4: Receive Approval and Your Medication** Once approved, you'll receive information about how to obtain your AYVAKIT. The program will arrange for your medication to be sent directly to you or to your pharmacy. ## What Happens After Approval? Good news: **you won't need to reauthorize annually**. Once approved, you can continue receiving assistance as long as your circumstances remain similar. However, if your income or insurance status changes significantly, let the program know. ## Additional Savings Options Beyond the patient assistance program, a **AYVAKIT savings card** is also available. This card can help reduce your out-of-pocket costs if you have commercial insurance. Ask your doctor or pharmacist about eligibility, or call the program number above. ## What About Insurance? The patient assistance program works with all insurance types: - **Uninsured**: You may qualify for full medication coverage - **Underinsured**: Partial assistance is possible - **High deductibles or copays**: If your out-of-pocket costs are unaffordable, the program can help bridge the gap Medicare and Medicaid patients can also apply. ## Getting Help If you have questions at any step, call **(888) 258-7768**. Program staff can help you understand eligibility, gather documents, and complete your application. They're there to help you succeed. ## Next Steps Don't let cost prevent you from accessing AYVAKIT. If your medication is unaffordable, reach out to the YourBlueprint Patient Assistance Program today. With a valid prescription and basic information, you could be receiving help soon.

Program information last verified: March 25, 2026