Astagraf XL

Indicated For

kidney transplant organ rejection prophylaxis

About This Medication

# Astellas Cares Patient Assistance Program Guide: How to Get Astagraf XL at Low or No Cost Astagraf XL (tacrolimus extended-release) is a critical immunosuppressant medication used to prevent organ rejection in kidney transplant patients, and the **Astellas Cares** program from manufacturer **Astellas Pharma US** helps eligible patients access it at no cost if uninsured or low-income.[3][5] This guide explains eligibility, application steps, and support options in simple terms to help you secure your medication affordably. ## About Astagraf XL **Astagraf XL** is an extended-release form of tacrolimus, a calcineurin-inhibitor that suppresses the immune system to prevent your body from rejecting a transplanted kidney.[1][9] It's typically taken once daily and must be used with other immunosuppressants. Without consistent use, rejection risks increase, making reliable access essential—especially since monthly costs can exceed **$800–$1,200** without assistance.[5] Common side effects include diarrhea, constipation, nausea, swelling, and tremors.[1] Serious risks involve infections, kidney damage, or high blood pressure—always discuss with your doctor. Do not take if allergic to tacrolimus. Inform your healthcare provider of all medications, as interactions are common.[1] ## Who Qualifies for Astellas Cares? The **Astellas Cares** program provides **Astagraf XL at no cost** to eligible patients, primarily those who are **uninsured or low-income**.[3][5] Exact income thresholds (e.g., Federal Poverty Level percentages) are not publicly detailed but typically align with programs offering aid up to 400–500% of the FPL for individuals or families—confirm your status during application.[5] U.S. residency is required, and you must have a valid prescription for Astagraf XL. **Key eligibility factors**: - Uninsured or underinsured with high out-of-pocket costs. - Household income-based (proof required). - Not eligible if covered by government insurance like Medicare/Medicaid in most cases (copay cards may apply instead).[5] - Transplant patients in need of ongoing therapy.[4] ## Income Eligibility Breakdown Specific thresholds for Astellas Cares are determined case-by-case, but patient assistance programs like this often use guidelines similar to those below (based on 2026 Federal Poverty Levels; adjust for your household size). Contact the program for precise limits.[5] | Household Size | Estimated Max Income (300% FPL) | Estimated Max Income (400% FPL) | Notes | |---------------|-------------------------------|-------------------------------|-------| | 1 (Individual) | $45,180 | $60,240 | Common entry point for uninsured | | 2 (Couple) | $61,320 | $81,760 | Add ~$16,140 per extra person at 300% | | 3 | $77,460 | $103,280 | Family examples; verify with program | | 4 | $93,600 | $124,800 | Larger families may qualify higher | *These are illustrative; actual eligibility may vary. Provide recent tax returns or pay stubs.[5]* ## Insurance Requirements **Astellas Cares** is best for **uninsured** or **low-income patients without adequate coverage**.[5] If you have **commercial insurance**, use the **Astagraf XL Copay Card** instead—it lowers costs to **$0 per fill** (up to **$3,000/year savings**).[3][5] **Medicare patients** generally cannot use copay cards but may qualify for Astellas Cares if income-eligible or explore Low-Income Subsidy (LIS/Extra Help) via SSA.[9] Government insurance often disqualifies from manufacturer PAPs—check details.[2][5] ## Step-by-Step Application Process 1. **Visit the website**: Go to **astellascares.com**.[3][5] 2. **Check eligibility**: Use their online tool or call for pre-screening. 3. **Gather documents**: Prepare proof of income (tax return, W-2s, pay stubs), prescription, proof of residency, and doctor's statement confirming need.[5] 4. **Complete application**: Fill out the form online or download/print. Your doctor/pharmacy may need to sign.[3] 5. **Submit**: Online, mail, or fax (details on site). No specific phone listed—use website contact form.[3] 6. **Follow up**: Track status via portal or email. Applications are free and straightforward, designed for patients like you.[5] ## Timeline and Delivery Processing typically takes **2–4 weeks**, though some approvals occur faster.[5] Once approved, medication ships **directly to your home or doctor's office** at **no cost** for a set supply period (e.g., 90 days).[3][5] Refills require reapplication or reauthorization—details provided upon approval. ## Alternatives if Denied or Ineligible - **Copay Card**: For commercial insurance—**$0 copay** up to limits.[3][5] - **Discount Cards**: GoodRx or SingleCare for cash pay, saving up to 90%.[2][5] - **Other PAPs**: PAN Foundation, HealthWell, or Patient Advocate Foundation for copays (income/hardship-based).[6][9] - **Generic Tacrolimus**: Cheaper immediate-release options; discuss with doctor.[5] - **Nonprofits**: American Kidney Fund for transplant meds.[5] - **Extra Help**: Medicare LIS if low-income.[9] **Biosimilar alternatives**: None currently available for Astagraf XL.[ ] ## Important Disclaimer This guide is for informational purposes only and based on publicly available data as of 2026—not official program rules. Eligibility, terms, and availability can change; always verify at **astellascares.com** or by contacting Astellas directly.[3][5] Consult your healthcare provider before starting/stopping Astagraf XL—missing doses risks organ rejection. Not medical or legal advice. Report side effects to FDA at 1-800-FDA-1088.[1] Word count: 1028.

Program information last verified: March 29, 2026