AMVUTTRA

Indicated For

ATTR-CM, hATTR-PN

About This Medication

# Alnylam Assist Patient Assistance Program Guide: How to Get AMVUTTRA at Low or No Cost ## About This Program The Alnylam Assist Patient Assistance Program (PAP) is a free program designed to help patients who cannot afford their AMVUTTRA (vutrisiran) medication. Alnylam, the manufacturer, offers this program to ensure that cost is never a barrier to accessing this important treatment. ## What Is AMVUTTRA? AMVUTTRA is a prescription medication used to treat two serious conditions: - **ATTR-CM** (Transthyretin Amyloid Cardiomyopathy) — a rare heart disease - **hATTR-PN** (Hereditary Transthyretin-mediated Amyloidosis with Polyneuropathy) — a rare nerve disease AMVUTTRA is an RNAi therapeutic, a type of advanced medicine that works by reducing harmful proteins in your body. It is given as an injection under the skin. ## Who Can Qualify? ### Income Eligibility Income limits vary based on your household size. Use this table as a general guide: | Household Size | Approximate Max Annual Income | |---|---| | 1 person | Varies (contact program) | | 2 people | Varies (contact program) | | 3 people | Varies (contact program) | | 4 people | Varies (contact program) | | 5+ people | Varies (contact program) | **Note:** Income thresholds vary and may be adjusted. Contact the program directly at **(833) 256-2748** to confirm your specific eligibility based on your household income and size. ### Insurance Status This program is **primarily for uninsured patients**. If you have insurance, you may still qualify in these situations: - Your insurance denies coverage for AMVUTTRA - Your copay or coinsurance is unaffordable - You are underinsured (have very high deductibles or limited coverage) If you have insurance, Alnylam may direct you to other assistance programs better suited to your situation. ## What You'll Need to Apply To apply, you will need: 1. **Alnylam Start Form** — This form is the main application document. Your doctor can help you get this, or you can request it when you call or visit the program website. 2. **Proof of income** — Recent tax return, pay stubs, or benefit statements 3. **Proof of residency** — Utility bill or lease agreement 4. **Insurance information** — If you have any coverage, include details 5. **Your contact information** — Phone number and mailing address ## How to Apply: Step-by-Step Instructions ### Step 1: Gather Your Documents Collect the required documents listed above. Ask your doctor's office to help you fill out the Alnylam Start Form if needed. ### Step 2: Choose How to Apply You can apply using any of these methods: - **Online:** Visit https://www.alnylamassist.com/amvuttra/financial-assistance and complete the online application - **Phone:** Call **(833) 256-2748** to speak with a program representative who can guide you through the process - **Fax:** Send your completed application and documents to **1-833-256-2747** - **Mail:** Contact the program for a mailing address ### Step 3: Submit Your Application Provide all required documents with your completed Start Form. Be as accurate and complete as possible to avoid delays. ### Step 4: Wait for Approval The program typically processes applications within **4-8 weeks**. You will be contacted once a decision is made. ### Step 5: Receive Your Medication If approved, AMVUTTRA will be **shipped directly to you** or your doctor's office. Most patients receive their medication within 1-2 weeks after approval. ## Timeline and What to Expect - **Application submission:** Same day - **Typical processing time:** 4-8 weeks - **Approval notification:** By phone or mail - **Medication delivery:** 1-2 weeks after approval If you don't hear back within 8 weeks, call **(833) 256-2748** to check on your application status. ## What If Your Application Is Denied? If your application is denied, ask the program: 1. Why your application was not approved 2. What information might help you reapply 3. Whether you can appeal the decision 4. What other assistance programs you might qualify for Many denials can be resolved by providing additional documentation or correcting information. ## Money-Saving Options Beyond the PAP ### Alnylam Assist Copay Card Even if you have insurance, the **Alnylam Assist Copay Card** may reduce your out-of-pocket costs. Visit https://www.alnylamassistcopay.com to learn more or request a card. ### State Assistance Programs Most states offer pharmaceutical assistance programs for low-income residents. Search your state's health department website or contact 211.org (dial 2-1-1 or visit online) for local resources. ### Non-Profit Organizations Organizations focused on amyloidosis, heart disease, or rare diseases may offer grants or financial assistance. Ask your doctor or social worker for recommendations. ## Important Information ### Reauthorization Contact the program if your circumstances change or if you need to renew your assistance after a certain period. ### Privacy and Confidentiality Your personal and financial information is kept confidential and used only to determine eligibility for the program. ### No Cost to You There is never a fee to apply for or use this patient assistance program. ## Contact Information **Alnylam Assist Patient Assistance Program** - **Phone:** (833) 256-2748 - **Fax:** 1-833-256-2747 - **Website:** https://www.alnylamassist.com/amvuttra/financial-assistance - **Hours:** Monday-Friday, typically 9 AM to 5 PM Eastern Time ## Legal Disclaimer This guide is for educational purposes only and does not constitute legal or medical advice. Program eligibility, benefits, and requirements are subject to change. For the most current and accurate information, contact the Alnylam Assist Patient Assistance Program directly or visit their official website. Always consult with your healthcare provider regarding your medication and treatment options.

Program information last verified: March 25, 2026