Alymsys

Indicated For

Metastatic colorectal cancer, Non-squamous non-small cell lung cancer, Recurrent glioblastoma, Metastatic renal cell carcinoma, Persistent/recurrent/metastatic cervical cancer, Epithelial ovarian/fallopian tube/primary peritoneal cancer

About This Medication

# Amneal PATHways Patient Guide: How to Get Alymsys (bevacizumab-maly) at Low or No Cost Alymsys (bevacizumab-maly) is a biosimilar to Avastin, used to treat certain cancers like colorectal, lung, kidney, and ovarian cancers by blocking blood vessel growth in tumors.[1][4] The **Amneal PATHways** program from Amneal Pharmaceuticals offers patient support, including the Patient Assistance Program (PAP) for **free medication** up to one year for eligible U.S. patients facing financial hardship.[1][2][3] ## Who Qualifies for Amneal PATHways and PAP? The program supports U.S. residents (including Puerto Rico and U.S. Virgin Islands) prescribed Alymsys.[2][5] It includes two main paths: - **PATHways Co-pay Program**: For **commercially insured** patients (not Medicare, Medicaid, or uninsured). Pay **as little as $0** per treatment. No income limits.[7] - **Patient Assistance Program (PAP)**: Free Alymsys for **uninsured, underinsured**, or those in financial hardship. Must meet income criteria and residency rules. Medicare Part D patients need to have spent at least **3% of annual household income** out-of-pocket on prescriptions.[3][9] **Key eligibility notes**: - U.S. resident only.[5] - Valid prescription required.[5] - Program determines exact income thresholds based on **household income** and Federal Poverty Level (FPL); call for details as specifics vary.[3][9][1] ## About Alymsys (bevacizumab-maly) **Alymsys** is an injectable biosimilar to Avastin (bevacizumab), approved for the same uses: metastatic colorectal cancer, non-small cell lung cancer, glioblastoma, renal cell carcinoma, cervical cancer, and epithelial ovarian/fallopian tube/primary peritoneal cancer.[4] It works by inhibiting vascular endothelial growth factor (VEGF), starving tumors of blood supply. Administered IV in a healthcare setting, typically every 2-3 weeks. Common side effects include high blood pressure, bleeding, and infusion reactions—discuss risks with your doctor.[4] As a **biosimilar**, Alymsys matches Avastin in safety, efficacy, and quality but may cost less.[1] The reference product is **Avastin**.[program details] ## Income Eligibility Breakdown Exact FPL percentages aren't publicly listed and depend on household size—contact the program for your situation.[3] General PAP criteria from Amneal programs: | Household Size | Estimated Max Income (e.g., 400-500% FPL)* | Medicare Part D Requirement | |---------------|---------------------------------------------|-----------------------------| | Individual | ~$60,000-$75,000 annually | ≥3% household income spent on Rx |[3][9] | Couple | ~$80,000-$100,000 | ≥3% household income spent on Rx |[3] | Family of 3 | ~$100,000-$125,000 | ≥3% household income spent on Rx |[3] | Family of 4 | ~$120,000-$150,000 | ≥3% household income spent on Rx |[3] *Estimates based on 2026 FPL; **call 1-877-764-9021** to confirm exact thresholds, as they 'meet program eligibility requirements.'[2][3][9] Co-pay program has **no income requirements**.[7] ## Insurance Requirements - **Commercial insurance**: Eligible for co-pay card ($0 copay possible).[7] - **Medicare Part D**: Eligible for PAP if out-of-pocket spend ≥3% income; not for co-pay program.[3][9] - **Uninsured/underinsured**: PAP primary option.[2] - **Medicaid/VA**: Generally ineligible.[7] PATHways specialists investigate benefits and explore options.[1][7] ## Step-by-Step Application Process 1. **Get Prescribed**: Doctor prescribes Alymsys and discusses PATHways.[1][4] 2. **Enroll in PATHways**: Call **866-426-6325** or visit provider portal; opt into SMS for updates.[1][2] 3. **Speak to Access Specialist**: They assess insurance, affordability, and PAP eligibility.[1][3] 4. **For PAP**: - Download/complete application (patient sections 1-3).[5][9] - Doctor completes/sends original signed prescription.[5] - Gather **financial docs** (tax returns, pay stubs, proof of Rx spend for Medicare).[5][9] - **Fax/mail** to: Amneal PAP, PO Box 220586, Charlotte, NC 28222 (Fax: 1-877-764-9022).[5] 5. **Follow Up**: Answer calls from 1-866-426-6325; save number.[1] Call **1-877-764-9021** (M-F, 8AM-5PM CST) for PAP support.[2] ## Timeline and Delivery - **Approval**: Varies; opt into SMS for status. PAP up to weeks for review.[1][5] - **Duration**: Free meds shipped to **home** for **up to 1 year**.[2][3][5] - **Renewal**: Program sends form before expiration.[5][9] ## Alternatives if Denied - **Appeal**: PATHways helps with insurer denials/PA appeals.[3] - **Co-pay switch**: If commercially insured.[7] - **Biosimilar alternatives**: Avastin (reference).[program details] - **Other resources**: Third-party aid via specialists.[1] - **Reapply**: Check eligibility changes.[2] ## Disclaimer This guide summarizes publicly available info as of 2026; eligibility/terms change. Not medical/financial advice. Confirm details with Amneal at 1-877-764-9021 or 866-426-6325. Consult your doctor. Program not insurance; limits apply.[1][2][5][7] (Word count: 950)

Program information last verified: March 30, 2026