Altuviiio

Indicated For

Hemophilia A

About This Medication

# HemAssist™ Patient Guide: How to Get ALTUVIIIO® at Low or No Cost ALTUVIIIO® (efanesoctocog alfa, also known as Antihemophilic Factor (Recombinant), Fc-VWF-XTEN Fusion Protein-ehtl) is a prescription medication used to treat hemophilia A in adults and children. HemAssist™, Sanofi's patient support program, offers financial help through its Patient Assistance Program (PAP), Copay Program, and Free Trial Program to make ALTUVIIIO® more affordable for eligible patients.[1][2][3] ## About ALTUVIIIO® and Hemophilia A Hemophilia A is a genetic bleeding disorder caused by a lack of functional factor VIII, a clotting protein in the blood. Without enough factor VIII, people with hemophilia A can experience frequent or spontaneous bleeding into joints, muscles, or other areas, leading to pain, swelling, and long-term joint damage.[4][10] **ALTUVIIIO®** is a **once-weekly factor VIII replacement therapy** designed for routine prophylaxis (preventing bleeds), on-demand treatment of bleeding episodes, and perioperative management (around surgery). Unlike standard factor VIII therapies limited by von Willebrand factor, ALTUVIIIO® uses proprietary Fc fusion technology to extend its half-life, providing high-sustained factor activity levels and superior bleed protection. Clinical trials (XTEND-1 Phase 3) showed a mean annualized bleeding rate (ABR) of 0.70 and median ABR of 0.0 for prophylaxis, with a 77% reduction in ABR compared to prior therapies.[6][8][9][10] It's FDA-approved for all ages, including expanded pediatric data confirming effectiveness in children.[8] Administered via intravenous infusion, typically once weekly for prophylaxis.[1][4] ## Who Qualifies for HemAssist™ Programs? HemAssist™ tailors support to your situation, working directly with you to identify eligibility. Programs include: - **Copay Program**: Reduces out-of-pocket costs to **as little as $0** for eligible commercially insured patients.[1][2] - **Free Trial Program**: First-time patients get a **30-day supply within 24-48 hours** with a valid prescription.[1][3][7] - **Patient Assistance Program (PAP)**: Free or low-cost ALTUVIIIO® for **uninsured, underinsured, or temporarily uninsured** patients.[1][2][3] **Key exclusions**: Programs are **not valid** for government-funded insurance like **Medicare (including Part D), Medicaid, Medigap, VA, DoD, TRICARE®, or state pharmaceutical assistance programs**. Sanofi may modify terms if insurance dilutes benefits. Not valid where prohibited by law.[1][2][3][7] ## Income Eligibility Breakdown Specific income thresholds (e.g., Federal Poverty Level percentages) are **not publicly detailed**; eligibility is determined case-by-case via benefits investigation. Contact HemAssist for personalized assessment.[1][3] Here's a general guide based on typical PAP structures (confirm with program): | Household Size | Estimated Max Annual Income (300% FPL example)* | Notes | |---------------|-----------------------------------------------|-------| | 1 (Individual) | ~$45,180 | Uninsured/underinsured prioritized [1] | | 2 (Couple) | ~$61,320 | Case-by-case review [3] | | 3 | ~$77,460 | Government insurance excludes [2] | | 4 | ~$93,600 | Add ~$16,140 per additional member | *Illustrative; actual varies. FPL 2026 estimates.[1][2] ## Insurance Requirements - **Commercial/Private Insurance**: Eligible for Copay Program (as low as $0 copay).[1][2] - **Uninsured/Underinsured/Temporary Loss**: PAP may provide free medication.[1][3] - **Government Programs (Medicare, Medicaid, etc.)**: **Ineligible** for all HemAssist financial aid.[2][3][7] HemAssist verifies coverage, navigates prior authorizations, and assists with appeals.[3][5][7] ## Step-by-Step Application Process 1. **Get Prescribed**: Discuss ALTUVIIIO® with your doctor. They complete the enrollment form.[5][6] 2. **Enroll in HemAssist**: Visit www.altuviiio.com/financial-support or call **1-855-MyALTUVIIIO (1-855-692-5888)**. Your doctor faxes the form to Sanofi Patient Services.[1][3][5] 3. **Benefits Investigation**: Case Manager reviews insurance (within 24 hours).[3][7] 4. **Choose Program**: Matched to Copay, Free Trial, or PAP.[1] 5. **Specialty Pharmacy**: Prescription sent; medication shipped.[5][7] 6. **Start Treatment**: Receive education, infusion training, and support.[1][3] Download form: altuviiio.com enrollment PDF.[5] ## Timeline and Delivery - **Free Trial**: 30-day supply in **24-48 hours**.[1][3][7] - **PAP/Copay Approval**: Varies; Case Manager contacts within 24 hours post-enrollment. Ongoing support for refills.[3][7] - **Delivery**: Via specialty pharmacy; HemAssist coordinates shipments and reimbursements.[7] Expect personalized timelines based on insurance verification.[1] ## Alternatives if Denied or Ineligible - **State Pharmaceutical Assistance**: Check state programs (if not using federal aid).[2] - **Other Foundations**: National Bleeding Disorders Foundation (bleeding.org) or hemophilia organizations for grants.[10] - **Generic/Biosimilars**: No biosimilars listed for ALTUVIIIO®; discuss standard factor VIII options with doctor.[9] - **Appeal**: HemAssist helps with insurance appeals.[3] - **Doctor Assistance**: HCP can explore samples or bridging therapies.[7] ## Important Disclaimer This guide is for informational purposes only and based on publicly available data as of 2026.[1][2] Eligibility, terms, and availability can change; Sanofi reserves the right to modify/terminate programs without notice.[1][2][5] Not medical advice—consult your healthcare provider. Programs not valid where prohibited. Income examples illustrative; verify directly with HemAssist at 1-855-692-5888 or altuviiio.com.[1][3] (Word count: 942)

Program information last verified: March 30, 2026