Aldurazyme

Indicated For

MPS I (Hurler, Hurler-Scheie, Scheie with moderate to severe symptoms)

About This Medication

# Sanofi Patient Assistance Program Patient Guide: How to Get Aldurazyme at Low or No Cost ## About This Program The **Sanofi Patient Assistance Program** is designed to help eligible patients access Aldurazyme (laronidase) at no cost when they cannot afford their medication or lack adequate insurance coverage. Sanofi, the manufacturer of Aldurazyme, offers this program to ensure that financial barriers do not prevent patients from receiving the treatment they need.[1][2] ## About Aldurazyme Aldurazyme (laronidase) is an enzyme replacement therapy used to treat mucopolysaccharidosis I (MPS I), a rare genetic disorder that affects the body's ability to break down certain complex sugars. This medication helps reduce symptoms and slow disease progression in eligible patients.[3] ## Who Qualifies for This Program? To be eligible for the Sanofi Patient Assistance Program, you must meet the following requirements:[1][2][4] - **Residency**: You must be a resident of the United States or U.S. territories - **Healthcare Provider**: You must be under the care of a licensed healthcare provider authorized to prescribe, dispense, and administer medicine - **Insurance Status**: You must have no insurance coverage, OR have commercial insurance or Medicaid but lack coverage or access to Aldurazyme, OR have Medicare Part B coverage without supplemental insurance - **Financial Need**: You must meet specific income requirements based on the Federal Poverty Level (see Income Eligibility section below) - **Medicaid Status**: If you may be eligible for Medicaid, you must provide documentation of Medicaid denial before being assessed for patient assistance ## Income Eligibility To qualify financially, your **annual household income must not exceed 400% of the current Federal Poverty Level (FPL)**.[4] This threshold varies based on household size and is updated annually. | Household Size | 2026 Federal Poverty Level | 400% of FPL (Approximate) | |---|---|---| | Individual | Contact program | Contact program | | Family of 2 | Contact program | Contact program | | Family of 3 | Contact program | Contact program | | Family of 4 | Contact program | Contact program | **Note**: Exact income thresholds change yearly. For current 2026 limits specific to your household size, call the program at **(800) 745-4447** or visit the Sanofi Patient Connection website to view Financial Eligibility Information.[4] ## Insurance Requirements The program is available to patients with various insurance situations:[1][2][6] - **Uninsured patients**: Those with no health insurance coverage - **Underinsured patients**: Those with commercial insurance or Medicaid but lacking coverage for Aldurazyme - **Medicare Part B patients**: Those with Medicare Part B coverage and no supplemental insurance who meet all other eligibility criteria **Important**: This program is **not valid** for patients whose prescriptions are covered by Medicaid, Medicare Part D, VA, DOD, TRICARE, or other federal or state programs. If you have coverage through these programs, you should work with your healthcare provider to access your medication through your existing insurance. ## How to Apply Applying for the Sanofi Patient Assistance Program is straightforward and involves these steps: ### Step 1: Obtain the Application You can get an application in two ways:[5] - **Download online**: Visit the Sanofi Patient Connection website and download the application form - **Request by phone**: Call **(800) 745-4447** toll-free to have an application mailed to you ### Step 2: Complete Your Information Fill out all required patient information on the application, including:[1][2] - Your full name, date of birth, and contact information - Your household income and family size - Your current insurance status - Sign and date the required **HIPAA consent** and **income verification** authorizations **Important**: Do not include medical records with your application. ### Step 3: Have Your Healthcare Provider Complete Their Section Bring the completed application to your doctor or healthcare provider. They must:[1][2] - Complete their section of the application - Sign and date the form - Verify they are authorized to prescribe, dispense, and administer Aldurazyme ### Step 4: Submit Your Application Your healthcare provider can submit the completed application (pages 2-3 only) using one of these methods:[1][2][5] - **By Fax**: 1-888-847-1797 - **By Mail**: Sanofi Patient Connection, PO Box 222138, Charlotte, NC 28222-2138 - **Provider Portal**: Healthcare providers can also submit through the online Provider Portal at visitspconline.com **Tip**: Ensure all information is complete and both you and your provider have signed the form. Missing information will delay processing. ## Timeline and What to Expect ### Processing Time Fully completed and signed applications are typically processed within **5-7 business days**.[5] If your application is missing information, processing will take longer as the program team will need to contact your healthcare provider to gather required details. ### After Approval If you are approved:[1][2] 1. You and your healthcare provider will receive a letter notifying you of enrollment 2. If you are a Medicare Part D patient, your plan sponsor will also receive notification 3. Your medication will be sent directly to your healthcare provider's office in approximately **5-7 business days** from approval 4. You will be enrolled for **12 months** of assistance (Medicare Part D patients are enrolled through the end of the calendar year) ### If You Are Denied If you do not qualify for the program, you and your healthcare provider will receive a letter explaining the reason for denial.[1] ## Reauthorization and Renewal If you need assistance beyond your initial 12-month enrollment period, you can **reapply on a yearly basis**.[5] Medicare Part D patients will be transitioned back to Medicare Part D at the beginning of each calendar year and can reapply if they continue to meet eligibility criteria. ## What If Your Application Is Denied? If your application is denied, review the denial letter carefully to understand the reason. Common reasons include:[1] - Income exceeding 400% of the Federal Poverty Level - Having insurance coverage that should cover the medication - Missing required documentation or signatures - Not meeting residency requirements If you believe the denial was made in error, contact the program at **(800) 745-4447** to discuss your situation. You may also explore other resources or assistance programs recommended by your healthcare provider. ## Important Disclaimers - This program is subject to change at any time at Sanofi's discretion - Any fees charged by third parties to complete your application are not required by or remitted to Sanofi - This program does not replace your health insurance; it is designed to supplement care for eligible uninsured or underinsured patients - Always consult with your healthcare provider about your treatment options and eligibility ## Contact Information For questions about the Sanofi Patient Assistance Program: - **Phone**: (800) 745-4447 (toll-free) - **Fax**: 1-888-847-1797 - **Mail**: Sanofi Patient Connection, PO Box 222138, Charlotte, NC 28222-2138 - **Website**: www.sanofipatientconnection.com

Program information last verified: March 30, 2026