AKYNZEO

Helsinn Cares Patient Support Program Patient Guide: How to Get AKYNZEO at Low or No Cost

AKYNZEO (netupitant/palonosetron) is a prescription medication used to prevent nausea and vomiting caused by cancer chemotherapy. The Helsinn Cares Patient Support Program helps uninsured or underinsured patients get AKYNZEO at low or no cost by providing free medication when you qualify.

About AKYNZEO

AKYNZEO combines two active ingredients: netupitant (300 mg) and palonosetron (0.5 mg) in capsule form. It works by blocking substances in your body that trigger nausea and vomiting, especially during chemotherapy treatment. It's typically taken as a single capsule about 30 minutes to 1 hour before receiving chemotherapy. Always follow your doctor's instructions for use. This program covers the oral capsules (NDC: 69639-101-01).[3][7]

AKYNZEO is important for cancer patients because chemotherapy often causes severe nausea, which can affect your ability to eat, rest, and tolerate treatment. Talk to your doctor if you experience side effects like headache, weakness, or indigestion.

Who Qualifies for the Program?

The program is designed for patients struggling to afford AKYNZEO due to lack of insurance coverage. Key eligibility factors include:

• Uninsured or underinsured patients who meet income guidelines (specific income thresholds are not publicly published; call the program for details).[1][7]
• U.S. citizens or residents.
• Valid prescription for AKYNZEO from a licensed physician.
• Proof of financial need.[7]

Medicare Part D patients: Contact the program directly, as some restrictions may apply. The program excludes certain Medicare enrollees but offers details upon inquiry.[1][2]

This assistance is not health insurance and cannot be used with government-funded programs in ways that violate rules.

Income Eligibility Breakdown

Exact income thresholds based on Federal Poverty Level (FPL) are not published publicly for this program. Income limits are typically set at 400-500% of FPL for a household, but you must verify by phone. Medical expenses may sometimes be deducted, though this is not confirmed.[7]

Here's a general example table of common PAP income guidelines (for illustration; call 1-844-357-4668 for Helsinn specifics):

Add ~$21,520 (400% FPL) or ~$26,900 (500% FPL) per additional person. These are U.S. 2026 estimates; actual program limits may differ. Social Security income is not always required on forms.[7]

Insurance Requirements

• Open to uninsured (no coverage) or underinsured (high copays/denials) patients.
• Include front/back copies of insurance cards for verification.[2]
• Medicare patients: Some exclusions for Part D enrollees; program provides co-pay assistance or reimbursement support where allowed. Fax Insurance Verification Request Form to 1-844-357-4669.[1][2][7]
• Commercial insurance: Program offers benefits investigation, prior authorization help, and appeals assistance.[2]

Step-by-Step Application Process

The program uses multiple application methods: phone, fax, or forms. Here's how to apply:

1. Get a prescription: Ask your doctor for AKYNZEO and discuss the Helsinn Cares program.

2. Gather documents:

   • Completed enrollment form (download from program or doctor obtains).
   • Prescription for AKYNZEO.
   • Proof of financial need (e.g., tax returns, pay stubs, bank statements).[7]
   • Insurance verification (cards, denial letters).[2]
   • Physician details: State license #, NPI, signature.[7]

3. Contact the program: Call (844) 357-4668 (1-844-HELSINN-U) for help, forms, or enrollment. Provider phone same.[1][2][7]

4. Submit: Fax to 1-844-357-4669 or mail to: Patient Support, 2250 Perimeter Park Drive Suite 300, Morrisville, NC 27560. Sign HIPAA authorization and patient consent for data sharing.[2][7]

5. Approval notification: Eligibility letter sent to both patient and provider.[7]

Patient and doctor signatures verify info accuracy; program may modify or discontinue anytime.[2]

Timeline and Delivery

• Processing time: Not specified; expect contact from a representative after submission.[6][7]
• Delivery method: Medication shipped to patient or physician's office free of charge.[7]
• Quantity: Not published; typically covers treatment cycle.
• Refills: Reauthorization required periodically; reapply as needed.[7]

Call for status updates. Expect prompt review similar to other programs (days to weeks).

Alternatives if Denied or Ineligible

• Independent foundations: Program may refer you (e.g., via Mercalis).[2]
• Co-pay savings card: Separate AKYNZEO Capsule Savings Program for eligible commercially insured patients.[3]
• RxAssist.org: Search other PAPs.[1]
• Physician samples or Early Access Programs for investigational needs (physician-submitted).[4][5]
• Generic antiemetics or other NK1/5-HT3 antagonists (discuss with doctor; no biosimilars listed).
• State programs or low-income clinics.

Contact Helsinn for referrals to funding sources.[2]

Important Disclaimer

This guide is for informational purposes based on publicly available data as of 2026. Helsinn reserves the right to change, modify, or end the program anytime without notice.[2] Eligibility not guaranteed. Consult your doctor and call (844) 357-4668 for latest details. Not tax or legal advice. Program excludes uses violating law. Word count: 1028.