Afstyla

Indicated For

hemophilia A

About This Medication

# CSL Behring Patient Assistance Program Patient Guide: How to Get Afstyla at Low or No Cost Afstyla (**lonoctocog alfa**) is a recombinant Factor VIII therapy designed for people with **hemophilia A**, helping to control and prevent bleeding episodes through on-demand treatment, routine prophylaxis, or perioperative management.[6][10] The **CSL Behring Patient Assistance Program** provides free or low-cost Afstyla to eligible uninsured or underinsured patients who meet strict financial criteria, ensuring access to this vital treatment when insurance falls short.[1][3][5] ## About Afstyla and Hemophilia A Hemophilia A is a genetic bleeding disorder caused by insufficient **Factor VIII**, a clotting protein essential for blood to coagulate properly. Without treatment, spontaneous or injury-related bleeds can damage joints, muscles, and organs. **Afstyla** stands out as the first single-chain recombinant Factor VIII, engineered for extended protection—offering 2-3 times longer half-life than traditional therapies in some cases.[10] It's FDA-approved for: - **On-demand treatment** to stop active bleeding episodes.[6] - **Routine prophylaxis** to reduce bleed frequency.[6] - **Perioperative management** during surgery.[6] *Note: Afstyla is not for von Willebrand disease.*[6] Administered via intravenous infusion, dosing is personalized by your doctor based on weight, bleed history, and activity level. Common side effects include headache, diarrhea, rash, and joint pain—discuss risks with your healthcare provider.[6] ## Who Qualifies? This program targets patients facing financial hardship due to lack of insurance or inadequate coverage. Key eligibility: - **Financial need**: Household income **below 250% of the Federal Poverty Level (FPL)**. No fixed thresholds for family size are specified; eligibility is assessed individually.[program details] - **Residency**: U.S. resident with proof.[program details] - **Insurance status**: Uninsured, underinsured, or limited coverage. **Government insurance (Medicare, Medicaid) excluded**, especially from co-pay assistance.[program details][4] ### Income Eligibility Breakdown Eligibility hinges on income < **250% FPL** for uninsured/underinsured. Use the table below for 2026 estimates (FPL updates annually; verify current guidelines via AFSTYLA Connect). | Household Size | 100% FPL (approx.) | 250% FPL Threshold (approx.) | |----------------|---------------------|------------------------------| | 1 (Individual) | $15,060 | $37,650 | | 2 (Couple) | $20,440 | $51,100 | | 3 | $25,820 | $64,550 | | 4 | $31,200 | $78,000 | *Add ~$5,380 per additional person for 100% FPL. Examples only—call (800) 676-4266 for exact qualification.*[program details] ## Insurance Requirements - **Eligible**: No insurance, underinsured (high copays/deductibles), or limited private coverage.[1][3][5] - **Ineligible**: Medicare, Medicaid, or other government programs. Co-pay program requires private commercial insurance and excludes government plans.[4][program details] Explore **AFSTYLA Connect** case managers for **Benefit Investigation**—they contact insurers to clarify coverage and costs.[1][4] Separate **Copaytion** program offers up to **$12,000/year** for eligible commercially insured patients.[3][4] **CSL Behring Assurance** provides product during coverage lapses, with points earned monthly.[1][3] ## Step-by-Step Application Process 1. **Contact AFSTYLA Connect**: Call **(800) 676-4266** (Mon-Fri, 8am-8pm ET) or visit afstyla.com/support. Case managers guide you.[1][2] 2. **Download/Request Form**: Get the **AFSTYLA Patient Referral Form** from your doctor or online.[4] 3. **Gather Documents**: - **Proof of income** (tax returns, pay stubs, W-2s).[program details] - **Proof of residency** (utility bill, lease).[program details] - **Proof of insurance status** (denial letter or insurance card showing limits).[program details] - **Valid prescription** from your physician.[program details] 4. **Submit**: Doctor completes referral; mail/fax or submit via case manager. Multiple methods available.[program details][4] 5. **Approval Wait**: Processing time varies (typically weeks); case managers provide updates.[1] 6. **Receive Medication**: Shipped directly to your home if approved.[program details] **Tip**: Enroll early in **Assurance Program** for lapse protection.[1] ## Timeline and Delivery - **Processing**: Not specified; expect 2-4 weeks based on similar programs—call for status.[1][program details] - **Supply**: Up to 3-month supply per approval.[5] - **Delivery**: Free shipping to patient.[program details] - **Reauthorization**: **Required**—resubmit docs periodically to continue.[program details] **Free Trial**: New patients may qualify via doctor referral.[2][3] ## If Denied or Alternatives - **Appeal**: Contact case manager to review denial reasons (e.g., income over limit).[1] - **Other CSL Programs**: **Copaytion** ($12k max, commercial insurance), **Assurance** (lapse coverage).[1][3][4] - **External Resources**: NeedyMeds, RxAssist, or hemophilia organizations like NHF.[8][9] - **No biosimilars** listed for Afstyla.[program details] - **Switch Therapies**: Transfer Assurance points from other CSL hemophilia products.[1] ## Important Disclaimer This guide summarizes publicly available info as of 2026 and program details.[1][3][program details] Eligibility, terms, and benefits can change—**always verify with CSL Behring at (800) 676-4266** or afstyla.com. Not legal/medical advice. Consult your doctor for treatment decisions. CSL Behring reserves rights to modify/terminate program. Income based on pre-tax household; exclusions apply. *(Word count: 950)*

Program information last verified: March 30, 2026