Afrezza
Generic: insulin human inhalation powder
Manufacturer: MannKind Corporation · Program: AfrezzaAssist Patient Support Program
Apply for assistanceFree to apply. Service from $40/month, payable only when your application is ready to submit.
Eligibility Criteria
Insurance Requirement
Commercially insured patients age 18+; not valid for Medicare, Medicaid, VA, DoD, TRICARE, or government-funded programs
Residency
US resident
Program Information
Processing Time
48 hours
Delivery Method
shipped to patient
Application Method
Online
Reauthorization
Required, annual
Indicated for
Diabetes mellitus type 1 and type 2
About This Medication
AfrezzaAssist Patient Support Program Patient Guide: How to Get Afrezza (insulin human inhalation powder) at Low or No Cost
AfrezzaAssist, offered by MannKind Corporation, helps eligible commercially insured adults access Afrezza—an ultra-rapid-acting inhaled insulin—at little to no cost. This guide explains eligibility, application steps, and more to make starting treatment easier.[1][10]
About Afrezza: A New Way to Manage Mealtime Blood Sugar
Afrezza (insulin human inhalation powder) is a prescription rapid-acting inhaled insulin for adults with type 1 or type 2 diabetes. Unlike injected insulins, you inhale it through a small, portable inhaler right at mealtime to control high blood sugar spikes.[1][3][4][7][10]
How Afrezza Works
Afrezza enters your lungs for ultra-rapid absorption, starting in about 10 minutes—faster than most injected rapid-acting insulins. This helps reduce post-meal highs and timing stress.[3][8] It's used with long-acting insulin for type 1 diabetes but not as a replacement.[1][10]
Key Dosing Basics (always follow your doctor's instructions):
- Insulin-naïve patients: Start with 4 units per meal.
- Switching from injections: Use a conversion chart (e.g., injected dose may need 1.5-2x adjustment).[1][3][10]
- Cartridges come in 4, 8, or 12 units; inhale one per cartridge, using multiples if needed.[2][6]
Step-by-Step Inhaler Use
- Load cartridge(s) into the Afrezza inhaler.
- Remove mouthpiece cover (keep level).
- Exhale fully away from inhaler.
- Inhale steadily and deeply.
- Hold breath ~10 seconds, exhale normally.
- Discard used cartridge.[1][2][3][6]
Important Safety Notes:
- Not for smokers (current or quit <6 months), those with lung disease (asthma/COPD), or kids under 18.
- Requires lung function test (spirometry) before starting.
- See full warnings in Medication Guide.[4][9][10]
Who Qualifies for AfrezzaAssist?
This program targets commercially insured patients age 18+. It's not valid for Medicare, Medicaid, VA, DoD, TRICARE, or other government programs.[program details]
Income Eligibility
No specific income thresholds are listed, making it accessible to many without strict financial cutoffs. Eligibility focuses on insurance type and age rather than household income.[program details]
| Eligibility Factor | Details |
|---|---|
| Age | 18 years and older |
| Insurance | Commercial/private only; excludes government plans |
| Income | No thresholds specified—broad access for eligible insured |
| Prescription | Valid Afrezza Rx from doctor |
| Residency | U.S. residents[program details] |
Insurance Requirements
You must have commercial insurance covering Afrezza. The program provides savings (often $0 copay up to a cap) but cannot be used with government insurance. Confirm coverage with your plan first—your pharmacy or insurer can help.[program details]
Step-by-Step Application Process
Applying is simple and online-focused. Here's how:
-
Get Prescribed: Ask your doctor for Afrezza. Discuss if it's right for your diabetes management.[1][7]
-
Visit the Site: Go to afrezzasavingscard.com to activate your savings card or enroll.[program details]
-
Fill Out Form: Provide your name, address, date of birth, insurance details, and pharmacy info. Your doctor may need to e-prescribe or complete a form.
-
Submit Online or Call: Use the website for fastest processing, or call (844) 323-7399 for help.[program details]
-
Approval: Expect a decision in about 48 hours. You'll get a savings card or confirmation digitally/mailed.[program details]
-
Fill at Pharmacy: Present card + Rx. Afrezza ships directly to you if part of free trial/supply offers.[program details][1]
Tips: Have insurance card ready. Program requires reauthorization periodically—set reminders.[program details]
Timeline and Delivery
- Processing: ~48 hours from submission.
- Delivery: Shipped free to your home (for eligible supplies); pharmacy fills ongoing Rx with savings.
- First Dose: Practice with your inhaler using provided guides.[program details][1][3]
What If You're Denied or Need Alternatives?
Common Denial Reasons:
- Government insurance.
- Under 18.
- No valid commercial coverage.
Next Steps:
- Appeal: Call (844) 323-7399 to review.
- Other Programs: Check NeedyMeds.org or Partnership for Prescription Assistance for income-based options (AfrezzaAssist has no income limits, but others might fit uninsured).
- Biosimilars/Alternatives: No biosimilars listed; talk to your doctor about injected rapid insulins like Humalog or Novolog.
- Manufacturer Contact: MannKind support for exceptions.[program details]
Refills and Reauthorization
Use your savings card at any pharmacy for refills. Reauthorization is required (e.g., annually)—renew online or by phone before expiration to avoid gaps.[program details]
Disclaimer
This guide is for informational purposes only and not medical advice. Eligibility, benefits, and terms can change—visit afrezzasavingscard.com or call (844) 323-7399 for latest details. Always consult your healthcare provider before starting Afrezza. Program void where prohibited by law. MannKind Corporation reserves rights to modify/amend.[program details][1][10]
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Program information last verified: March 30, 2026
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