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Diabetes

Afrezza

Generic: insulin human inhalation powder

Manufacturer: MannKind Corporation  ·  Program: AfrezzaAssist Patient Support Program

Apply for assistance

Free to apply. Service from $40/month, payable only when your application is ready to submit.

Eligibility Criteria

Insurance Requirement

Commercially insured patients age 18+; not valid for Medicare, Medicaid, VA, DoD, TRICARE, or government-funded programs

Residency

US resident

Program Information

Processing Time

48 hours

Delivery Method

shipped to patient

Application Method

Online

Reauthorization

Required, annual

Indicated for

Diabetes mellitus type 1 and type 2

About This Medication

AfrezzaAssist Patient Support Program Patient Guide: How to Get Afrezza (insulin human inhalation powder) at Low or No Cost

AfrezzaAssist, offered by MannKind Corporation, helps eligible commercially insured adults access Afrezza—an ultra-rapid-acting inhaled insulin—at little to no cost. This guide explains eligibility, application steps, and more to make starting treatment easier.[1][10]

About Afrezza: A New Way to Manage Mealtime Blood Sugar

Afrezza (insulin human inhalation powder) is a prescription rapid-acting inhaled insulin for adults with type 1 or type 2 diabetes. Unlike injected insulins, you inhale it through a small, portable inhaler right at mealtime to control high blood sugar spikes.[1][3][4][7][10]

How Afrezza Works

Afrezza enters your lungs for ultra-rapid absorption, starting in about 10 minutes—faster than most injected rapid-acting insulins. This helps reduce post-meal highs and timing stress.[3][8] It's used with long-acting insulin for type 1 diabetes but not as a replacement.[1][10]

Key Dosing Basics (always follow your doctor's instructions):

  • Insulin-naïve patients: Start with 4 units per meal.
  • Switching from injections: Use a conversion chart (e.g., injected dose may need 1.5-2x adjustment).[1][3][10]
  • Cartridges come in 4, 8, or 12 units; inhale one per cartridge, using multiples if needed.[2][6]

Step-by-Step Inhaler Use

  1. Load cartridge(s) into the Afrezza inhaler.
  2. Remove mouthpiece cover (keep level).
  3. Exhale fully away from inhaler.
  4. Inhale steadily and deeply.
  5. Hold breath ~10 seconds, exhale normally.
  6. Discard used cartridge.[1][2][3][6]

Important Safety Notes:

  • Not for smokers (current or quit <6 months), those with lung disease (asthma/COPD), or kids under 18.
  • Requires lung function test (spirometry) before starting.
  • See full warnings in Medication Guide.[4][9][10]

Who Qualifies for AfrezzaAssist?

This program targets commercially insured patients age 18+. It's not valid for Medicare, Medicaid, VA, DoD, TRICARE, or other government programs.[program details]

Income Eligibility

No specific income thresholds are listed, making it accessible to many without strict financial cutoffs. Eligibility focuses on insurance type and age rather than household income.[program details]

Eligibility FactorDetails
Age18 years and older
InsuranceCommercial/private only; excludes government plans
IncomeNo thresholds specified—broad access for eligible insured
PrescriptionValid Afrezza Rx from doctor
ResidencyU.S. residents[program details]

Insurance Requirements

You must have commercial insurance covering Afrezza. The program provides savings (often $0 copay up to a cap) but cannot be used with government insurance. Confirm coverage with your plan first—your pharmacy or insurer can help.[program details]

Step-by-Step Application Process

Applying is simple and online-focused. Here's how:

  1. Get Prescribed: Ask your doctor for Afrezza. Discuss if it's right for your diabetes management.[1][7]

  2. Visit the Site: Go to afrezzasavingscard.com to activate your savings card or enroll.[program details]

  3. Fill Out Form: Provide your name, address, date of birth, insurance details, and pharmacy info. Your doctor may need to e-prescribe or complete a form.

  4. Submit Online or Call: Use the website for fastest processing, or call (844) 323-7399 for help.[program details]

  5. Approval: Expect a decision in about 48 hours. You'll get a savings card or confirmation digitally/mailed.[program details]

  6. Fill at Pharmacy: Present card + Rx. Afrezza ships directly to you if part of free trial/supply offers.[program details][1]

Tips: Have insurance card ready. Program requires reauthorization periodically—set reminders.[program details]

Timeline and Delivery

  • Processing: ~48 hours from submission.
  • Delivery: Shipped free to your home (for eligible supplies); pharmacy fills ongoing Rx with savings.
  • First Dose: Practice with your inhaler using provided guides.[program details][1][3]

What If You're Denied or Need Alternatives?

Common Denial Reasons:

  • Government insurance.
  • Under 18.
  • No valid commercial coverage.

Next Steps:

  • Appeal: Call (844) 323-7399 to review.
  • Other Programs: Check NeedyMeds.org or Partnership for Prescription Assistance for income-based options (AfrezzaAssist has no income limits, but others might fit uninsured).
  • Biosimilars/Alternatives: No biosimilars listed; talk to your doctor about injected rapid insulins like Humalog or Novolog.
  • Manufacturer Contact: MannKind support for exceptions.[program details]

Refills and Reauthorization

Use your savings card at any pharmacy for refills. Reauthorization is required (e.g., annually)—renew online or by phone before expiration to avoid gaps.[program details]

Disclaimer

This guide is for informational purposes only and not medical advice. Eligibility, benefits, and terms can change—visit afrezzasavingscard.com or call (844) 323-7399 for latest details. Always consult your healthcare provider before starting Afrezza. Program void where prohibited by law. MannKind Corporation reserves rights to modify/amend.[program details][1][10]

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Program information last verified: March 30, 2026

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