Actoplus Met
Generic: pioglitazone HCl + metformin HCl
Manufacturer: Takeda Pharmaceuticals America, Inc. · Program: Takeda Patient Assistance Program
Apply for AssistanceEligibility Criteria
Insurance Requirement
Uninsured; no private or public health insurance with prescription coverage
Residency
legal US resident
Income Threshold
Up to 300% FPL
income must be ≤ 300% of poverty guideline
Program Information
Processing Time
2-4 weeks
Delivery Method
shipped to patient or physician office
Application Method
Reauthorization
Required — every 12 months
Typically Required Documents
ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.
- Completed application signed by patient, physician, and pharmacist
Indicated For
Type 2 Diabetes
About This Medication
# Takeda Patient Assistance Program Patient Guide: How to Get Actoplus Met at Low or No Cost Actoplus Met (pioglitazone HCl + metformin HCl) is a prescription medication used to help control **type 2 diabetes** in adults, when diet and exercise alone are not enough. This guide explains how the **Takeda Patient Assistance Program** can provide **Actoplus Met for free** if you qualify, making it easier to manage your health without high costs. ## About Actoplus Met **Actoplus Met** combines two active ingredients: **pioglitazone** (a thiazolidinedione that helps your body use insulin better) and **metformin** (a biguanide that reduces glucose production in the liver and improves insulin sensitivity). It's typically taken twice daily with meals to lower blood sugar levels and reduce the risk of diabetes complications like heart disease, kidney problems, or nerve damage. Always follow your doctor's instructions, as dosage depends on your condition—common strengths are 15 mg/500 mg or 15 mg/850 mg. **Important**: This is not insulin and won't work for type 1 diabetes. Discuss side effects like weight gain, swelling, or stomach upset with your doctor. ## Who Qualifies for the Program? The **Takeda Patient Assistance Program** (also called Help at Hand) helps **uninsured U.S. residents** get Takeda medicines like Actoplus Met **at no cost**. Key requirements include:[1][2][4] - A valid prescription from a **U.S.-licensed physician**. - **U.S. residency** (including territories). - **No prescription coverage** through private insurance, Medicare Part D (with exceptions), Medicaid, or other programs—or coverage that doesn't pay for your Takeda med.[1][9] - **Household income at or below 300% of the Federal Poverty Level (FPL)**.[2] **Special note for Medicare patients**: If your income is below 150% FPL, apply for Medicare's **Extra Help** first and include a denial letter. Above 150% FPL, no denial needed.[2] All applications are reviewed **case-by-case**.[1] ## Income Eligibility Breakdown Eligibility is based on **total household income** (before taxes) compared to **300% of the FPL**. The FPL changes yearly; check current guidelines at [www.aspe.hhs.gov/poverty-guidelines](https://aspe.hhs.gov/poverty-guidelines) or call the program. Here's a sample table for **2026 continental U.S.** (Alaska/Hawaii higher; add ~$5,000–$10,000 per person): | Household Size | 100% FPL | 300% FPL (Max Eligible) | |---------------|----------|-------------------------| | 1 | $15,060 | **$45,180** | | 2 | $20,440 | **$61,320** | | 3 | $25,820 | **$77,460** | | 4 | $31,200 | **$93,600** | | +1 person | +$5,380 | **+$16,140** | **Proof needed**: Pay stubs, tax returns, W-2s, or benefit letters. Last year's tax return often required if filed.[9] Program verifies on case-by-case basis.[1] ## Insurance Requirements You must be **uninsured for prescriptions** or have **insufficient coverage** for Actoplus Met. No private insurance, Medicare Part D coverage, Medicaid, TRICARE, etc.[1][9][10] If you have some coverage but it doesn't cover this med fully, explain on the form. **Medicare exception**: Apply for Extra Help first if <150% FPL.[2] Government programs may disqualify you unless denied.[1] ## Step-by-Step Application Process Applications are **by mail** (fax possible via doctor).[4][8] Download from [helpathandpap.com](https://www.helpathandpap.com) or call **(800) 830-9159** (Mon–Fri, 8am–8pm ET).[1][10] **Do not use stamped signatures**—originals required.[1][5] 1. **Get the form**: Patient completes Sections 1–2 (personal info, income). Attach **proof of income**.[1] 2. **Doctor fills out**: Sections 3–4 (prescription, medical need). Doctor signs.[1][4] 3. **Pharmacist signs**: If required on form.[provided data] 4. **Patient authorizes**: Sign Sections 5–6. Legal rep can sign (note relationship).[1] 5. **Submit**: Doctor faxes to **1-800-497-0928** or mail to **Takeda Patient Assistance Program, P.O. Box 5727, Louisville, KY 40255-0727**.[4][8][9] Include all docs—**incomplete apps delay processing**.[1][4] **Tip**: Call (800) 830-9159 for help or mailed form.[1][4] ## Timeline and Delivery - **Review**: 3–5 business days (up to 7 days per some docs).[1][4] - **Notification**: Letter to you/doctor on approval/denial.[1] - **Processing to meds**: Overall **2–4 weeks** from submission.[provided data] - **Delivery**: Free meds shipped to **your home or doctor's office**.[provided data] - **Supply**: Typically 1–3 months per shipment; **reauthorization required** annually or as needed.[provided data][1] Track status by calling (800) 830-9159.[1] ## Alternatives if Denied or No Other Options - **Reapply** with updated docs if circumstances change.[1] - **Extra Help** (Medicare Part D low-income subsidy): [medicare.gov/extrahelp](https://www.medicare.gov/extrahelp).[2] - **NeedyMeds/RxAssist**: Search [needymeds.org](https://needymeds.org) or [rxassist.org](https://rxassist.org) for generics or state programs. - **Generic alternatives**: Pioglitazone/metformin combos (cheaper; ask doctor). No biosimilars listed.[provided data] - **Takeda co-pay programs**: If insured, check [takedapatientsupport.com](https://www.takedapatientsupport.com).[3][7] - **Patient Access Network (PAN) Foundation** or state pharma aid. ## Disclaimer This guide is for informational purposes based on program details as of 2026 and search data.[1][2][4] **Eligibility, guidelines, and forms change**—verify with Takeda at (800) 830-9159 or [helpathandpap.com](https://www.helpathandpap.com). Not medical/financial advice. Consult your doctor before changing meds. Takeda may update income limits or rules. Free meds while supplies last; case-by-case approval. Not guaranteed.
Program information last verified: March 30, 2026
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