Actimmune

Indicated For

Chronic Granulomatous Disease, Severe Malignant Osteopetrosis

About This Medication

# Horizon By Your Side Patient Guide: How to Get Actimmune at Low or No Cost Actimmune (interferon gamma-1b) is a prescription medication used to reduce serious infections in chronic granulomatous disease (CGD) and delay disease progression in severe malignant osteopetrosis. The **Horizon By Your Side** program from Horizon Therapeutics helps eligible underinsured or uninsured patients access **Actimmune** at low or no cost through financial assistance, insurance navigation, and support services.[1][2][4] ## About Actimmune **Actimmune** is an injectable medicine given subcutaneously, typically three times a week. It boosts the immune system to fight infections in people with **chronic granulomatous disease (CGD)**, a genetic disorder where white blood cells can't kill certain bacteria and fungi effectively. It also helps patients with **severe malignant osteopetrosis**, a rare bone disease that can lead to fractures, anemia, and vision loss.[4][5][7] **Common side effects** include flu-like symptoms (fever, chills, fatigue), headache, rash, nausea, and injection site reactions. Serious risks involve liver issues, blood disorders, or kidney problems—your doctor will monitor blood tests every 3 months and liver function monthly if starting before age 1. Always follow your doctor's instructions and report side effects.[1][4][5] This guide focuses on the **Horizon By Your Side** program, which pairs you with a **Clinical Nurse Educator (CNE)** for one-on-one help with insurance, logistics, and treatment education.[1][3] ## Who Qualifies? The program supports **underinsured** (high copays or deductibles) and **uninsured** patients prescribed Actimmune. It provides financial assistance, benefits investigation, prior authorization help, and appeals for denials. Commercially insured patients may qualify for a separate copay program.[1][2] **Key eligibility:** - Valid Actimmune prescription for FDA-approved uses (CGD or osteopetrosis). - U.S. resident (program complies with state prescription rules).[2] - Willing to provide insurance details and sign authorizations.[1][2] Government-insured patients (e.g., Medicare, Medicaid) may have limited eligibility for some services—call to confirm.[2] ## Income Eligibility Specific income thresholds (e.g., Federal Poverty Level percentages) are **not publicly detailed** in program materials. Eligibility focuses on insurance status rather than strict income limits, targeting underinsured/uninsured patients who meet financial need criteria assessed during enrollment.[1][2] | Household Size | Income Threshold | Notes | |---------------|------------------|-------| | Individual | Not specified | Assessed case-by-case for financial hardship. | | Couple | Not specified | Underinsured/uninsured prioritized. | | Family of 3 | Not specified | Contact program for personalized review. | | Family of 4+ | Not specified | No fixed FPL % listed; financial assistance available. | **Tip:** Your CNE will review your situation confidentially. Even without exact limits, many patients qualify if costs are a barrier.[1] ## Insurance Requirements - **Uninsured:** Eligible for free medication shipped to you or your doctor's office. - **Underinsured:** Help with copays, prior authorizations (PA), and appeals. - **Commercially insured:** Separate copay assistance. - **Medicare/Medicaid:** Limited support; not all services apply—program checks eligibility.[1][2] The team starts with a **Benefits Investigation (BI)** within 1-2 business days, summarizing coverage, PA needs, and out-of-pocket costs.[1] ## Step-by-Step Application Process 1. **Get Prescribed:** Ask your doctor for Actimmune and discuss Horizon By Your Side. 2. **Complete Patient Enrollment Form (PEF):** Download from horizonbyyourside.com or ask your doctor. Include: - Your info (name, address, DOB). - Insurance details + front/back copies. - Diagnosis and prescription (dose, quantity). - Doctor signature.[2] 3. **Sign Patient Authorization:** Authorize Horizon to handle insurance, benefits, and pharmacy on your behalf (HIPAA-compliant).[2] 4. **Fax to 1-877-305-7706:** Your doctor faxes the form. (Phone: 1-844-469-4297 for help, Mon-Fri 9AM-8PM ET).[1][2] 5. **Enrollment Confirmation:** Team contacts you with a CNE assignment. BI results follow quickly.[1] 6. **Approval & Start:** If eligible, medication ships. CNE guides injection training and refills.[3] **Pro Tip:** Start early—insurance steps like PA can take time.[1] ## Timeline and Delivery - **BI Results:** 1-2 business days.[1] - **Full Processing:** Varies by insurance; appeals add time. - **Delivery:** Free shipping to patient home or doctor's office via specialty pharmacy (e.g., Accredo).[2] Your CNE tracks everything and answers questions.[1][3] ## If Denied or Alternatives - **Appeal Help:** Program assists with letters and PA resubmissions.[1] - **Other Options:** - State assistance programs. - Generic/biosimilar alternatives: None available for Actimmune.[2] - Independent foundations (e.g., Patient Access Network). - Doctor can explore samples or payment plans. Contact your CNE immediately if denied—they specialize in next steps.[1] ## Disclaimer This guide is for informational purposes only and not medical advice. Eligibility, benefits, and terms can change—verify with Horizon By Your Side (1-844-469-4297). Horizon Therapeutics does not guarantee coverage or assistance. Consult your doctor for treatment decisions. Report side effects to FDA at 1-800-FDA-1088. Program excludes government-insured where prohibited. © Horizon Therapeutics (based on 2026 info).[1][2][4]

Program information last verified: March 25, 2026