← Find a medication
Other Specialties

Actigall

Generic: ursodiol

Manufacturer:  ·  Program:

Apply for assistance

Free to apply. Service from $40/month, payable only when your application is ready to submit.

Eligibility Criteria

Insurance Requirement

See program details

Residency

US residency required

Program Information

Processing Time

2–4 weeks

Delivery Method

Varies by program

Application Method

Online

Indicated for

primary biliary cholangitis

About This Medication

Patient Guide: How to Get Ursodiol (Actigall) at Low or No Cost

Important Information About Ursodiol Assistance

Unfortunately, there is currently no active manufacturer prescription assistance program (PAP) for ursodiol (Actigall). However, this does not mean you cannot access affordable medication. This guide explains alternative resources and strategies to help you obtain ursodiol at reduced or no cost.

About Ursodiol (Actigall)

Ursodiol is a bile acid medication used to treat two main conditions:

  • Gallstones: Helps dissolve certain types of gallstones in patients who cannot have surgery
  • Primary Biliary Cholangitis (PBC): An autoimmune liver disease where ursodiol slows disease progression

This medication works by reducing the amount of cholesterol produced by your liver and decreasing cholesterol absorption in your intestines. It typically requires long-term use, making affordability an important consideration.

Why There's No Active Manufacturer Program

Ursodiol has been available as a generic medication for many years. Most manufacturers of generic drugs do not maintain patient assistance programs, as the medications are typically available at lower costs through generic alternatives. However, you have several other options to reduce your out-of-pocket costs.

Alternative Resources for Affordable Ursodiol

1. Generic Medication Pricing

Generic ursodiol is significantly cheaper than brand-name Actigall. Ask your doctor to prescribe the generic version if they haven't already. Prices vary by:

  • Pharmacy location
  • Dosage strength
  • Quantity per prescription
  • Your insurance coverage

Typical generic ursodiol costs range from $20-$100 per month without insurance, depending on these factors.

2. Pharmacy Discount Programs

Many pharmacies offer their own discount programs:

  • GoodRx: Free service comparing prices across pharmacies and offering coupons
  • SingleCare: Discount program with free membership
  • RxSaver: App-based price comparison and coupons
  • Prescription manufacturer coupons: Check the manufacturer's website directly
  • Pharmacy loyalty programs: CVS, Walgreens, Walmart, and local pharmacies often have savings programs

3. State Pharmaceutical Assistance Programs

Many states offer programs to help uninsured and underinsured residents afford medications. These programs have varying income requirements and eligibility criteria. Contact your state health department or visit your state's website to learn about programs available to you.

4. NeedyMeds.org

This free resource provides comprehensive information about:

  • State pharmaceutical assistance programs
  • Disease-specific foundations offering aid
  • Hospital charity care programs
  • Other medication assistance resources

5. Disease-Specific Organizations

If you have primary biliary cholangitis, organizations dedicated to liver disease may offer financial assistance or guidance:

  • American Liver Foundation
  • Primary Biliary Cholangitis Organization
  • Other PBC support groups

6. Hospital Financial Assistance and Charity Care

If you receive ursodiol through a hospital system, ask about their financial assistance programs. Many hospitals have funds available for patients who cannot afford medications.

7. Medicare/Medicaid Programs

  • Medicare: If you qualify for Medicare, you may have prescription drug coverage through Part D
  • Medicaid: Income and asset limits vary by state; check your state's Medicaid program
  • Extra Help Program: Federal assistance for Medicare beneficiaries with limited income/resources

8. Patient Assistance from Compounding Pharmacies

Some compounding pharmacies offer lower prices or payment plans. Ask your insurance company or healthcare provider for referrals.

Income Eligibility Information

While there's no manufacturer PAP, state and federal programs typically use these income guidelines:

Household SizeFederal Poverty Level (2024)200% of FPL250% of FPL
1$15,060$30,120$37,650
2$20,440$40,880$51,100
3$25,820$51,640$64,550
4$31,200$62,400$78,000
5$36,580$73,160$91,450
6$41,960$83,920$104,900
7$47,340$94,680$118,350
8$52,720$105,440$131,800

Your eligibility depends on your specific state or federal program.

Step-by-Step Instructions to Find Assistance

Step 1: Compare Pharmacy Prices

  1. Get your prescription from your doctor
  2. Visit GoodRx.com or SingleCare.com
  3. Enter your medication (ursodiol), dosage, and quantity
  4. Compare prices at local pharmacies
  5. Use available coupons at checkout

Step 2: Check Your Insurance

  • Review your insurance plan's formulary
  • Confirm if ursodiol is covered and what your copay is
  • Ask about prior authorization requirements
  • Inquire about mail-order pharmacy discounts

Step 3: Explore State Programs

  1. Visit your state health department website
  2. Search for "pharmaceutical assistance program"
  3. Review eligibility requirements
  4. Gather required documents (income verification, proof of residency)
  5. Complete application online or by mail

Step 4: Contact NeedyMeds.org

  1. Visit NeedyMeds.org
  2. Enter your state and medication
  3. Review all available assistance options
  4. Follow specific program application instructions

Step 5: Ask Your Healthcare Provider

  • Tell your doctor about cost concerns
  • Ask if they have samples available
  • Request generic alternatives
  • Discuss dose adjustments if appropriate
  • Ask for referrals to social workers or patient advocates

Timeline and Delivery

Timelines vary significantly based on which resource you use:

  • Pharmacy discounts: Immediate (same-day use of coupons)
  • State programs: 2-8 weeks for approval
  • Insurance coverage: Depends on plan (typically immediate if covered)
  • Assistance organizations: 2-6 weeks

Delivery also varies:

  • Most pharmacy discounts allow you to fill at any participating pharmacy
  • Insurance coverage is filled through your preferred pharmacy
  • State programs may mail medications or provide authorization codes

What to Do If You're Denied Assistance

  1. Ask why you were denied: Request specific reasons in writing
  2. Appeal the decision: Most programs allow appeals with additional information
  3. Try alternative resources: Move to the next option on your list
  4. Contact your doctor: They may know about additional resources or samples
  5. Reach out to patient advocates: Many hospitals and clinics have social workers who specialize in finding assistance
  6. Consider disease-specific organizations: For PBC patients, these groups may have specific assistance options

Important Reminders

  • Don't delay treatment: If cost is preventing you from taking your medication, talk to your doctor immediately
  • Verify websites: Only visit official pharmaceutical company sites and government websites to avoid scams
  • Ask questions: There's no such thing as a silly question when it comes to medication costs
  • Update your information: Reapply to programs if your income or circumstances change
  • Generic is the same: Generic ursodiol is just as effective as brand-name Actigall

Legal Disclaimer

This guide is educational and does not constitute medical or legal advice. Eligibility requirements, program availability, and income thresholds change regularly. Always verify current requirements directly with programs and consult with your healthcare provider about your specific situation. The information provided is current as of the publication date but may change without notice.

Program information last verified: March 25, 2026

Ready to apply for Actigall assistance?

ProvisionRX manages the complete application process. Start your application in about 15 minutes.

Start My ApplicationBrowse All Medications

Need help finding a program?